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Editorial
. 2024 Oct 1;210(7):861-863.
doi: 10.1164/rccm.202407-1414ED.

Is Pulmonary Vascular Resistance in Acute Respiratory Distress Syndrome the Judge Defining Recruitment versus Overdistention with Positive End-Expiratory Pressure?

Michael R Pinsky  1 , Alain Mercat  2
Affiliations
Editorial

Is Pulmonary Vascular Resistance in Acute Respiratory Distress Syndrome the Judge Defining Recruitment versus Overdistention with Positive End-Expiratory Pressure?

Michael R Pinsky et al. Am J Respir Crit Care Med. .
No abstract available

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Figures

Figure 1.
Figure 1.
The theoretical effect of adding 10 cm H2O positive end-expiratory pressure (PEEP) to both pulmonary vascular resistance and lung volume. In all subjects, PEEP will increase end-expiratory lung volume. But in subjects whose response to PEEP was primarily alveolar recruitment (left side of the curve), pulmonary vascular resistance decreases, whereas in subjects without recruitable alveolar units, only overdistention occurs (right side of the curve), increasing pulmonary vascular resistance and impeding right ventricular function.
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References

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