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Review
. 2024 Oct;154(4):874-881.
doi: 10.1016/j.jaci.2024.08.008. Epub 2024 Aug 21.

Increasing awareness regarding the relationship between environmental exposures and allergic disease

Ellen R Conroy  1 , Rachel Peterson  2 , Wanda Phipatanakul  1 , William J Sheehan  3
Affiliations
Review

Increasing awareness regarding the relationship between environmental exposures and allergic disease

Ellen R Conroy et al. J Allergy Clin Immunol. 2024 Oct.

Abstract

This review highlights studies from the past 3 years that add to the understanding of the impact of environmental exposures on allergic disease. These include aeroallergens, air quality, prenatal or early-life exposures, and occupational exposures. Recent studies have focused on the relationship between the environment, the microbiome, and allergic disease, and new therapeutic options have also been reviewed. Lastly, there has been significant recent research improving our knowledge of the link between health disparities and environmental exposures. These scientific advances have resulted in a better understanding that sets the foundation for current and future research dedicated to improving health outcomes by modifying environmental exposures.

Keywords: Environment; aeroallergens; air quality; asthma; health disparities; microbiome.

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Conflict of interest statement

Disclosure statement Supported by the National Institutes of Health (grants T32 AI007512 and K24 AI106822). Disclosure of potential conflict of interest: W. Phipatanakul has consulting relationships with and receives clinical trial support from Genentech, Novartis, AstraZeneca, Regeneron, and Sanofi. W. J. Sheehan consults for Regeneron and receives clinical trial support from Merck. Ther rest of the authors declare that they have no relevant conflicts of interest.