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. 2024 Aug 22;24(1):437.
doi: 10.1186/s12872-024-04098-1.

Association between personality type and patient-reported outcomes (PRO) in patients with atrial fibrillation

Qing Yan #  1 , Jiaqi Liang #  1 , Yide Yuan  1 , Yuan Li  1 , Jiali Fan  1 , Wenhuan Wu  2 , Pan Xu  3 , Qunrang Wang  4 , Jiahong Xue  5   6
Affiliations

Association between personality type and patient-reported outcomes (PRO) in patients with atrial fibrillation

Qing Yan et al. BMC Cardiovasc Disord. .

Abstract

Background: Atrial Fibrillation (AF) is known to be associated with a negative emotional state. Patient-reported outcomes (PROs) are important tools for evaluating the endpoints of AF management. This study aims to examine the correlation between personality types and PROs in patients with AF.

Methods: All included subjects were newly diagnosed with AF fewer than one month, and their personality types were assessed using the Eysenck Personality Questionnaire (EPQ). Quality of life (QoL) was measured using the Atrial Fibrillation Effect on Quality of Life (AFEQT) questionnaire. Anxiety and depression were assessed using the General Anxiety Scale (GAD-7) and the 9-item Patient Health Questionnaire (PHQ-9), respectively. We constructed stepwise linear regression analyses for factors related to the QoL and emotional state in patients with AF.

Results: A total of 531 AF patients completed the survey and were categorized into four groups based on their personality types. Of these patients (mean age: 67.12 ± 10.93 years, 50.28% male), 357 (67.23%) had paroxysmal AF, and 16.95% (n = 90) had a sanguine personality. Compared to patients with other personality types, those with a sanguine personality had the highest average AFEQT scores (P < 0.001) and the lowest scores of GAD-7 and PHQ-9 scales (P < 0.05). Furthermore, multiple linear regression analyses suggested that sanguine personality was also independently associated with better QoL and emotional states (P < 0.05).

Conclusion: There is a significant association between the personality types and PROs in AF patients.

Keywords: Anxiety; Atrial fibrillation; Depressed; Patient-reported outcomes (PRO); Personality types; Quality of life (QoL).

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Conflict of interest statement

The authors declare no competing interests.

Figures

Fig. 1
Fig. 1
Characterization of four personality types
Fig. 2
Fig. 2
Subject screening procedure
Fig. 3
Fig. 3
AFEQT overall scores and sub-scales score in AF patients with different personality types. (a): The total scores of AFEQT questionnaire in AF patients with different personality types. (b) (c) (d): The scores of the AFEQT sub-scale in AF patients with different personality types
Fig. 4
Fig. 4
Emotional states of AF patients with different personality types. (a): Scores of the GAD-7 scale in patients with different personality types. (b): Scores of the PHQ-9 scale in patients with different personality types
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