Algorithms in allergy: An algorithm for alpha-Gal syndrome diagnosis and treatment, 2024 update

U Darsow¹, A Gelincik², U Jappe^{3

4}, T A Platts-Mills⁵, D Ünal², T Biedermann¹

Affiliations

¹ Department of Dermatology and Allergy Biederstein, TUM School of Medicine and Health, Technical University of Munich, Munich, Germany.
² Division of Immunology and Allergic Diseases, Department of Internal Medicine, Istanbul Faculty of Medicine, Istanbul University, Istanbul, Turkey.
³ Division of Clinical and Molecular Allergology, Research Center Borstel, Airway Research, Center North (ARCN), Member of the German Center for Lung Research, Borstel, Germany.
⁴ Interdisciplinary Allergy Outpatient Clinic, Department of Pneumology, University of Luebeck, Luebeck, Germany.
⁵ School of Medicine, Department of Medicine, Division of Asthma, Allergy, and Immunology, University of Virginia, Charlottesville, Virginia, USA.

U Darsow et al. Allergy. 2024 Nov.

. 2024 Nov;79(11):3169-3172.

doi: 10.1111/all.16291. Epub 2024 Aug 22.

U Darsow¹, A Gelincik², U Jappe^{3

4}, T A Platts-Mills⁵, D Ünal², T Biedermann¹

¹ Department of Dermatology and Allergy Biederstein, TUM School of Medicine and Health, Technical University of Munich, Munich, Germany.
² Division of Immunology and Allergic Diseases, Department of Internal Medicine, Istanbul Faculty of Medicine, Istanbul University, Istanbul, Turkey.
³ Division of Clinical and Molecular Allergology, Research Center Borstel, Airway Research, Center North (ARCN), Member of the German Center for Lung Research, Borstel, Germany.
⁴ Interdisciplinary Allergy Outpatient Clinic, Department of Pneumology, University of Luebeck, Luebeck, Germany.
⁵ School of Medicine, Department of Medicine, Division of Asthma, Allergy, and Immunology, University of Virginia, Charlottesville, Virginia, USA.

No abstract available

References

1. Platts‐Mills TA, Hilger C, Jappe U, et al. Carbohydrate epitopes currently recognized as targets for IgE antibodies. Allergy. 2021;76(8):2383‐2394.
1. Platts‐Mills T. Sensitisation of Forest workers to the oligosaccharide galactose alpha‐1, 3‐galactose (alpha‐gal) is strongly associated with tick bites but not with evidence of tick borne infections. Infect Dis (Lond). 2022;54(8):580‐582.
1. Fischer J, Lupberger E, Hebsaker J, et al. Prevalence of type I sensitization to alpha‐gal in forest service employees and hunters. Allergy. 2017;72(10):1540‐1547.
1. Hilger C, Fischer J, Wölbing F, Biedermann T. Role and mechanism of galactose‐alpha‐1,3‐galactose in the elicitation of delayed anaphylactic reactions to red meat. Curr Allergy Asthma Rep. 2019;19(1):3.
1. Levin M, Apostolovic D, Biedermann T, et al. Galactose α‐1,3‐galactose phenotypes. Lessons from various patient populations. Ann Allergy Asthma Immunol. 2019;122(6):598‐602.