Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2024 Aug 10;11(8):ofae447.
doi: 10.1093/ofid/ofae447. eCollection 2024 Aug.

Opportunities for Enhanced Public Health Surveillance via Molecular Detection and Sequencing of Diverse Respiratory Viruses From Self-collected SARS-CoV-2 Antigen Test Swabs

Kat Schmidt  1   2 , Simon D Pollett  1   2 , Stephanie A Richard  1   2 , Vivian Hogan  1   2 , Emily Hone  1   2 , Jennifer Rothenberg  1   2 , Rezalina Tant  1   2 , Michele Wayman  1   2 , Chantele Friend  1   2 , Kamala Thapa  1   2 , Lola Ulomi  1   2 , Julian Davies  1   2 , Amber Michel  1   2 , Timothy H Burgess  1 , Robert J O'Connell  1 , Mark P Simons  1 , Drake H Tilley  3 , Anthony C Fries  4 , Rhonda E Colombo  1   2
Affiliations

Opportunities for Enhanced Public Health Surveillance via Molecular Detection and Sequencing of Diverse Respiratory Viruses From Self-collected SARS-CoV-2 Antigen Test Swabs

Kat Schmidt et al. Open Forum Infect Dis. .

Abstract

We sequenced and genotyped severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), influenza, adenovirus, and respiratory syncytial virus, among other pathogens, from residual anterior nasal swabs self-collected for rapid SARS-CoV-2 antigen testing at the US Naval Academy. This is a key proof-of-concept for an acute respiratory infection surveillance approach, which could leverage prevalent SARS-CoV-2 antigen self-testing.

Keywords: SARS-CoV-2; human influenza; public health surveillance; respiratory tract infection; whole-genome sequencing.

PubMed Disclaimer

Conflict of interest statement

Potential conflicts of interest. All authors: no reported conflicts.

References

    1. GBD 2019 Diseases and Injuries Collaborators . Global burden of 369 diseases and injuries in 204 countries and territories, 1990–2019: a systematic analysis for the Global Burden of Disease Study 2019 [published correction appears in Lancet 2020; 396:1562]. Lancet 2020; 396:1204–22. - PMC - PubMed
    1. Murray J, Cohen AL. Infectious Disease Surveillance. In: Quah Stella R, ed. International Encyclopedia of Public Health. 2nd ed. Vol 4: Academic Press, 2017:222–9.
    1. Guh A, Reed C, Gould LH, et al. Transmission of 2009 pandemic influenza A (H1N1) at a public university—Delaware, April–May 2009. Clin Infect Dis 2011; 52:S131–7. - PubMed
    1. Biggs HM, Lu X, Dettinger L, Sakthivel S, Watson JT, Boktor SW. Adenovirus-associated influenza-like illness among college students, Pennsylvania, USA. Emerg Infect Dis 2018; 24:2117–9. - PMC - PubMed
    1. Arons MM, Hatfield KM, Reddy SC, et al. Presymptomatic SARS-CoV-2 infections and transmission in a skilled nursing facility. N Engl J Med 2020; 382:2081–90. - PMC - PubMed