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Case Reports
. 2024 Jul 23;16(7):e65212.
doi: 10.7759/cureus.65212. eCollection 2024 Jul.

Mucormycosis in an Immunocompetent Patient Recovering From Dengue Fever

Sushmitha D J  1 , Kalyan Kumar Reddy Annapureddy  2 , Nishan Poojary  1 , Santhosh Balapanga  3 , Bindu Kumari  2
Affiliations
Case Reports

Mucormycosis in an Immunocompetent Patient Recovering From Dengue Fever

Sushmitha D J et al. Cureus. .

Abstract

Mucormycosis is a rare yet aggressive fungal infection. Despite its rarity, India has experienced a surge in cases during the post-COVID-19 era. The high mortality rate associated with this infection necessitates early diagnosis, intervention, and aggressive treatment. Typically, it is observed in immunocompromised patients, where the disease progresses rapidly and leads to unfavorable outcomes. However, occurrences in previously healthy individuals are not uncommon. Dengue has been occasionally associated with mucormycosis in the post-recovery phase. This case report highlights the importance of heightened clinical suspicion and early intervention in patients with recent dengue infections and chronic sinus conditions. It explores potential risk factors, such as dengue-related immune alterations, environmental exposures, and anatomical alterations that may contribute to the development of mucormycosis in otherwise healthy individuals.

Keywords: amphotericin b and posaconazole; case report; chronic rhinosinusitis; deviated nasal septum; immunocompetent; mucormycosis; post dengue.

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Conflict of interest statement

Human subjects: Consent was obtained or waived by all participants in this study. Conflicts of interest: In compliance with the ICMJE uniform disclosure form, all authors declare the following: Payment/services info: All authors have declared that no financial support was received from any organization for the submitted work. Financial relationships: All authors have declared that they have no financial relationships at present or within the previous three years with any organizations that might have an interest in the submitted work. Other relationships: All authors have declared that there are no other relationships or activities that could appear to have influenced the submitted work.

Figures

Figure 1
Figure 1. The image shows a coronal CT scan of the paranasal sinuses without contrast, revealing an isodense mass lesion in the right maxillary region. There is patchy bony destruction with scattered intraosseous air foci present in the superior wall of the right maxillary sinus.
Figure 2
Figure 2. Axial T2-weighted MRI image without contrast showing hyperintense mucosal thickening and intrasinus hypointense contents in the right maxillary sinus.
Figure 3
Figure 3. The image shows hyaline, broad, ribbon-like aseptate hyphae with wide-angle branching.
Figure 4
Figure 4. Axial T1-weighted post-contrast image showing a heterogeneous enhancement pattern in the right maxillary sinus and premaxillary region.
Figure 5
Figure 5. Axial T1-weighted pre-contrast image
See this image and copyright information in PMC

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