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Comment
. 2024 Oct;28(5):1961-1967.
doi: 10.1007/s10029-024-03134-5. Epub 2024 Aug 23.

A nomogram prediction model for postoperative seroma/hematoma in elderly subjects after TAPP

Yongxiang Ge  1 , Yang Zhou  1 , Jian Liu  1 , Weijian Shen  1 , Hailiang Gu  1 , Guochang Cheng  2
Affiliations
Comment

A nomogram prediction model for postoperative seroma/hematoma in elderly subjects after TAPP

Yongxiang Ge et al. Hernia. 2024 Oct.

Abstract

Background: Formation of seroma/hematoma is one of the most common postoperative complications following laparoscopic inguinal hernia repair. This study aimed to identify risk factors associated with seroma/hematoma and construct a prediction model.

Methods: Elderly subjects undergoing laparoscopic Transabdominal preperitoneal Patch Plasty (TAPP) were included in this study. The observation endpoint was set as the occurrence of seroma/hematoma within 3 months after TAPP surgery. Independent risk factors were identified through preliminary univariate screening and binary logistic regression analysis. These risk factors were then used to construct a nomogram predictive model using R software.

Results: A total of 330 patients were included in the analysis, of which 51 developed seroma/hematoma, resulting in an incidence rate of 15.5%. Obesity (OR: 3.54, 95%CI: 1.45-8.66, P = 0.006), antithrombotic drug use (OR: 2.73, 95%CI: 1.06-7.03, P = 0.037), C-reactive protein (CRP) ≥ 8 (OR: 2.72, 95%CI: 1.04-7.10, P = 0.041, albumin/fibrinogen ratio (AFR) < 7.85 (OR: 2.99, 95%CI: 1.28-7.00, P = 0.012), and lymphocyte/monocyte ratio (LMR) < 4.05 (OR: 12.62, 95%CI: 5.69-28.01, P < 0.001) were five independent risk factors for seroma/hematoma. The nomogram model has well predictive value for seroma/hematoma, with an AUC of 0.879.

Conclusions: The nomogram model based on obesity, antithrombotic drug, CRP, AFR, and LMR has a proved good predictive value and it has potential in clinical practice.

Keywords: Inguinal hernia; Nomogram model; Postoperative seroma/Hematoma; Risk factor.

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References

    1. Kingsnorth A, LeBlanc K (2003) Hernias: inguinal and incisional. Lancet 362:1561–1571. https://doi.org/10.1016/S0140-6736(03)14746-0 - DOI - PubMed
    1. Perez AJ, Campbell S (2022) Inguinal hernia repair in older persons. J Am Med Dir Assoc 23:563–567. https://doi.org/10.1016/j.jamda.2022.02.008 - DOI - PubMed
    1. (2018) International guidelines for groin hernia management. Hernia 22:1–165. https://doi.org/10.1007/s10029-017-1668-x
    1. Li J, Gong W, Liu Q (2019) Intraoperative adjunctive techniques to reduce seroma formation in laparoscopic inguinal hernioplasty: a systematic review. Hernia 23:723–731. https://doi.org/10.1007/s10029-019-01903-1 - DOI - PubMed
    1. Tamme C, Garde N, Klingler A, Hampe C, Wunder R, Köckerling F (2005) Totally extraperitoneal inguinal hernioplasty with titanium-coated lightweight polypropylene mesh: early results. Surg Endosc 19:1125–1129. https://doi.org/10.1007/s00464-004-8219-0 - DOI - PubMed

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