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. 2024 Oct;20(4):411-415.
doi: 10.1007/s13181-024-01026-9. Epub 2024 Aug 23.

Biostatistics and Epidemiology for the Toxicologist: Likelihood Ratios

Gar Ming Chan  1 , Mark K Su  2
Affiliations

Biostatistics and Epidemiology for the Toxicologist: Likelihood Ratios

Gar Ming Chan et al. J Med Toxicol. 2024 Oct.

Abstract

Likelihood ratios compare two values (i.e., case rates) in order to illustrate the magnitude of the difference between the two. This ratio increases the confidence one can have in a diagnostic test from a different vantage point than that of sensitivity and specificity. The calculations of likelihood ratios are presented along with a simplified approach. Likelihood ratios are another tool the toxicologist should employ in their understanding of statistics and probability.

Keywords: Bayes Theorem; Likelihood Ratio; Probability.

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Conflict of interest statement

None

References

    1. Sahagun BE, Williams C, Su MK. Biostatistics and Epidemiology Principles for the Toxicologist: The “Testy” Test Characteristics Part I-Sensitivity and Specificity. J Med Toxicol. 2023;19(1):40–4. - PMC - PubMed
    1. Williams C, Sahagun BE, Su MK. Biostatistics and Epidemiology Principles for the Toxicologist: The “Testy” Test Characteristics Part II: Positive Predictive Value and Negative Predictive Value. J Med Toxicol. 2023;19(3):298–302. - PMC - PubMed
    1. Haynes RB, Sackett DL, Guyatt GH, Tugwell P. Clinical epidemiology: how to do clinical practice research. 3rd ed. USA: Lippincott Williams & Wilkins; 2005. pp. 273–322.

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