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. 1985 Feb;161(2):820-2.
doi: 10.1128/jb.161.2.820-822.1985.

Evidence that the 5' end of lac mRNA starts to decay as soon as it is synthesized

V J Cannistraro, D Kennell

Evidence that the 5' end of lac mRNA starts to decay as soon as it is synthesized

V J Cannistraro et al. J Bacteriol. 1985 Feb.

Abstract

By monitoring the decay of the first 16% of the beta-galactosidase message, we showed that the 5' end started to decay before the 3' end was completed and at a rate equivalent to that of the whole molecule. Thus, decay was neither from 3' to 5' nor from random internal fragmentation but rather proceeded in a net 5' to 3' direction.

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