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Review
. 2024 Oct;154(4):847-860.
doi: 10.1016/j.jaci.2024.08.011. Epub 2024 Aug 22.

Cleaning indoor air-what works for respiratory health: An updated literature review and recommendations

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Review

Cleaning indoor air-what works for respiratory health: An updated literature review and recommendations

Nicole M Robertson et al. J Allergy Clin Immunol. 2024 Oct.

Abstract

Indoor air pollution is a growing public health concern globally and is associated with increased respiratory symptoms and morbidity. Individuals spend most of their time indoors, and pollutant-related health effects are often driven by the indoor environment. Understanding effective interventions to improve indoor air quality and their impact on respiratory outcomes is key to decreasing the burden of air pollution for high-risk populations across the life-span. This review applies a hierarchy of interventions framework specific to respiratory health effects and focuses on recent studies of interventions to improve indoor air quality among high-risk populations with chronic respiratory disease published in the past 3 years. While policy and source control interventions are likely the most effective and equitable approaches to improve indoor air quality and benefit population health, these were less extensively investigated. Engineering interventions, such as air cleaner interventions, were the most widely studied. Several studies, including those focused on asthma and chronic obstructive pulmonary disease, demonstrated improvement in symptoms and medication receipt with interventions in both home- and school-based settings. Combined multilevel interventions with engineering and behavioral interventions led to improved respiratory outcomes in some, but not all, studies. Placing the recent work in the context of the broader literature, we identify gaps in research. Further research is needed to understand intervention effectiveness over time and an increased focus on policy and source control interventions that can mitigate risk in vulnerable populations.

Keywords: Air cleaner; air pollution; air quality; environmental risk; interventions; systematic review.

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Conflict of interest statement

Disclosure statement N.R. received a Johns Hopkins Physician Scientist Program microgrant. A.Q. was funded by the Division of Pulmonary and Critical Care T32 (National Institutes of Health [NIH] project 2T32HL007534-41). S.R. was supported by the National Heart, Lung, and Blood Institute (award K23HL164151). The BREATHE Children Center is supported by the National Institute of Environmental Health Sciences of the NIH (award P2CES033415). Disclosure of potential conflict of interest: The authors declare that they have no relevant conflicts of interest.

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