Conflicts of interest Dr Grimes has served as a clinical investigator and/or consultant for Galderma, Clinuvel, L'Oreal, Johnson & Johnson, LaserOptek, Mother Science, VYNE Therapeutics, RAPT Therapeutics, Incyte, Pfizer, AbbVie/Allergan, SkinBetterScience, and Medscape. Dr Kyei is a speaker for Abbvie, Lilly, Pfizer, and Proctor & Gamble. Dr Alexis has served as a consultant and/or advisory board for Leo, Galderma, Pfizer, Sanofi-Regeneron, Dermavant, Beiersdorf, Ortho, L'Oreal, BMS, Bausch health, UCB, Vyne, Arcutis, Janssen, Allergan, Almirall, Abbvie, Amgen, VisualDx, Eli Lilly, Swiss American, Cutera, Cara, EPI, Incyte, Castle, Apogee, Canfield, and Alphyn. Dr Elbuluk has served as a consultant for Incyte, VisualDx, La Roche Posay, Beiersdorf, and Unilever. She has served on advisory boards for Allergan, Eli Lilly, Galderma, Incyte, Pfizer, Janssen, L'Oreal, and McGraw Hill. She has been a speaker for La Roche Posay, Medscape. Dr Shapiro has served as a clinical investigator and consultant for Pfizer. He has served as a consultant for Lilly, 30 Madison, Lumenis B, DS Laboratories, and holds stock options for Replicel Life Sciences. [Reprint requests: Pearl E Grimes]. Drs Drake, Tatarinova, and Ms Dias have no conflicts of interest to declare.