Topical Oxygen Therapy for Promoting Healing After Implant Placement Using Blue® M Gel: A Report of Two Cases

Abstract

Peri-implant diseases, such as peri-implant mucositis and peri-implantitis, are distinguished by a gradual onset of inflammation within the peri-implant mucosa, resulting in bone resorption and, ultimately, implant failure. Topical oxygen therapy is recognized for its ability to decrease inflammation, enhance blood flow, and provide a bacteriostatic effect. Utilizing oxygen-based therapy products as a local treatment for peri-implant mucositis and peri-implantitis may lead to comparable clinical results as traditional local adjuncts such as chlorhexidine, antibiotics, and antibacterial agents. This article discusses two case reports in which the Blue® M gel was utilized. In the first case, a 50-year-old female patient with a decade-long history of betel quid chewing and missing upper right first and second molars was treated with Blue® M gel to reduce the chances of peri-implantitis and promote healing following a first-stage surgical procedure for implant placement. In the second case, Blue® M gel was applied to a 56-year-old female patient who experienced pain and inflammation one week after the initial surgical procedure for implant placement to restore the missing posterior teeth on the lower right side. The use of the Blue® M gel led to accelerated healing in both instances.

Keywords: chlorhexidine; healing; mucositis; oxygen therapy; peri-implantitis.

Figure 1. Missing 16 and 17 in the upper right quadrant (A). Implants placed successfully with primary stability (B). Application of Blue® M gel (C). Soft tissue healing at the three-week follow-up (D).

Figure 2. Tearing of the mucosa at the second-week follow-up (A). Clean-up of the site and resuturing (B). Application of Blue®M gel (C). Follow-up at two weeks after Blue®M gel application (D).