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. 2024 May 20:48:15.
doi: 10.11604/pamj.2024.48.15.42881. eCollection 2024.

Prevalence and determinant factors of depression and anxiety in people with chronic kidney disease: a Moroccan cross-sectional study

Amina Chrifi Alaoui  1 , Mohammed Omari  1 , Noura Quarmich  1 , Omar Kouiri  2 , Basmat Amal Chouhani  2   3 , Mohammed Berraho  1   3 , Nabil Tachfouti  1   3 , Tarik Sqalli Houssaini  2   3 , Samira El Fakir  1   3
Affiliations

Prevalence and determinant factors of depression and anxiety in people with chronic kidney disease: a Moroccan cross-sectional study

Amina Chrifi Alaoui et al. Pan Afr Med J. .

Abstract

Introduction: the chronic kidney disease (CKD), is associated with various psychiatric conditions and poorer quality of life. The main objective of this study is to estimate the prevalence of depression and anxiety among CKD patients and to assess their determinant factors.

Methods: this is a cross-sectional study in a Moroccan university hospital. Patients aged ≥18 years and followed for more than one year for a stage 3 to 5 CKD, not under renal replacement therapy (RRT) were included. The data were collected using a questionnaire and the hospital anxiety and depression scale (HADS). The association between depression and anxiety sub-scores and the estimated glomerular filtration rate (eGFR) was assessed using simple and multiple linear regression.

Results: eighty-three patients (mean age 61.7 ± 14.1 years, and 61.4% were women), were included. Regarding the stages of CKD, 10.7% were in stage 3, 52.2% in stage 4, and 25% in stage 5 of CKD. The median of the depression sub-score was 5.00 (IQR (2.00; 10.0)). The median of the depression sub-score was 5.00 (IQR (2.00; 10.09)), and the median of the anxiety sub-score was 6.00 (IQR (4.00; 9.00)). It also shows that 22.0% of patients had depression (stage 4 = 23.8%, stage 5 = 36.8%) and 22.2% had anxiety (stage 4 = 26.2%, stage 5 = 33.3%). Both depression and anxiety scores were significantly associated with the eGFR before (p<0.001, p= 0.001 respectively) and after adjustment (p=0.001, p=0.002 respectively).

Conclusion: according to this study depression and anxiety are strongly related to eGFR.

Keywords: Depression; anxiety; chronic kidney disease; prevalence.

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Conflict of interest statement

The authors declare no competing interests.

Figures

Figure 1
Figure 1
prevalence of depression and anxiety according to chronic kidney disease (CKD) stage
See this image and copyright information in PMC

References

    1. KDIGO 2012 Clinical Practice Guideline for the Evaluation and Management of Chronic Kidney Disease Official Journal of the International Society of Nephrology. 2013 - PubMed
    1. Ginieri-Coccossis M, Theofilou P, Synodinou C, Tomaras V, Soldatos C. Quality of life, mental health and health beliefs in haemodialysis and peritoneal dialysis patients: investigating differences in early and later years of current treatment. BMC Nephrol. 2008 Nov 14;9:14. - PMC - PubMed
    1. Aggarwal HK, Jain D, Pawar S, Yadav RK. Health-related quality of life in different stages of chronic kidney disease. QJM Int J Med. 2016;109(11):711–716. - PubMed
    1. Aggarwal HK, Jain D, Dabas G, Yadav RK. Prevalence of Depression, Anxiety and Insomnia in Chronic Kidney Disease Patients and their Co-Relation with the Demographic Variables. Pril (Makedon Akad Nauk Umet Odd Med Nauki) 2017 Sep 1;38(2):35–44. - PubMed
    1. Bikbov B, Purcell CA, Levey AS, Smith M, Abdoli A, Abebe M, et al. Global, regional, and national burden of chronic kidney disease, 1990-2017: a systematic analysis for the Global Burden of Disease Study 2017. Lancet. 2020 Feb 29;395(10225):709–733. - PMC - PubMed

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