Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2024 Apr;17(Suppl 1):S100-S111.
doi: 10.5005/jp-journals-10005-2805.

Herbal Mouthrinses for Prevention of Dental Caries in Children and Adolescents: A Systematic Review

Affiliations

Herbal Mouthrinses for Prevention of Dental Caries in Children and Adolescents: A Systematic Review

Ankita M Saikia et al. Int J Clin Pediatr Dent. 2024 Apr.

Abstract

The primary aim of this study was to evaluate the effectiveness of herbal mouthrinses (HMR) on caries prevention in children and adolescents. In addition, this systematic review assessed its effectiveness in remineralization of white spot lesions, reduction of halitosis, and improving gingival and periodontal health in orthodontic patients and patients with special healthcare needs (SHCN). A comprehensive bibliographic search was conducted in PubMed, Cochrane Central, EMBASE, AMED, ProQuest, CINAHL, AYUSH, Digital Helpline for Ayurveda Research Articles (DHARA), and Clinical Trial Gov databases. A total of 3,918 titles were identified during the initial search. Of these, 32 studies were selected for quality assessment. A total of 5,038 participants from 10 countries were thus included in this review, with 22 (66.7%) studies conducted in India. All included studies were published between 2004 and 2021. Included studies investigated the effect of HMR on caries increments, which record decayed, missing, filled (DMF) [International Caries Detection and Assessment System (ICDAS)], decayed, missing, filled teeth/surfaces (DMFT/S), and incipient caries. Changes in bacterial count (Streptococcus mutans and Lactobacillus) and alterations in levels of Candida albicans from saliva or plaque samples were also reported. The effect of HMR on gingival and plaque indices among adolescents undergoing orthodontic treatment and children with SHCN was reported in two studies. The variance in the HMR formula across studies, short follow-up period, and limiting grade of evidence do not allow for conclusive evidence of the efficacy of HMR. This warrants high-quality randomized controlled trials (RCTs) with longer intervention periods involving children under 6 years to yield more conclusive results.

How to cite this article: Saikia AM, Sivasubramanian A, MS M, et al. Herbal Mouthrinses for Prevention of Dental Caries in Children and Adolescents: A Systematic Review. Int J Clin Pediatr Dent 2024;17(S-1):S100-S111.

Keywords: Caries prevention; Herbal mouthrinse; Herbs; Streptococcus mutans; Systematic review.

PubMed Disclaimer

Conflict of interest statement

Source of support: This systematic review was a funded project by the Indian Council of Medical Research (ICMR), Grant no.5/7/1708/CH/Adhoc/RBMCH2020. Conflict of interest: NoneConflict of interest: None

Figures

Fig. 1:
Fig. 1:
Preferred Reporting Items for Systematic Reviews and Meta-Analysis flow to illustrate the screening process
Fig. 2:
Fig. 2:
Risk of bias graph
Fig. 3:
Fig. 3:
Risk of bias summary

Similar articles

References

    1. Amruthesh S. Dentistry and ayurveda – III (basics-ama, immunity, ojas, rasas, etiopathogenesis and prevention) Indian J Dent Res. 2007;18(3):112–119. doi: 10.4103/0970-9290.33786. - DOI - PubMed
    1. Hirschfeld I. Toothbrush, Its Use and Abuse: A Treatise on Preventive Dentistry and Periodontia as Related to Dental Hygiene. New York: Dental Items of Interest Publishing; 1939.
    1. Jagtap AG, Karkera SG. Extract of Juglandaceae regia inhibits growth, in vitro adherence, acid production and aggregation of Streptococcus mutans. J Pharm Pharmacol. 2000;52(2):235–242. doi: 10.1211/0022357001773751. - DOI - PubMed
    1. Pai MR, Acharya LD, Udupa N. Evaluation of antiplaque activity of Azadirachta Indica leaf extract gel-A 6-week clinical study. J Ethnopharmacol. 2004;90(1):99–103. doi: 10.1016/j.jep.2003.09.035. - DOI - PubMed
    1. Song JH, Yang TC, Chang KW, et al. In vitro effects of a fraction separated from Polygonum cuspidatum root on the viability, in suspension and biofilms, and biofilm formation of mutans streptococci. J Ethnopharmacol. 2007;112(3):419–425. doi: 10.1016/j.jep.2007.03.036. - DOI - PubMed

LinkOut - more resources