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. 2024 Oct 1;81(10):1098-1099.
doi: 10.1001/jamaneurol.2024.2612.

Association of Cardiovascular Events With Spouse's Subsequent Dementia

Toshiaki Komura  1 , Yusuke Tsugawa  2   3 , Elizabeth Rose Mayeda  4 , M Maria Glymour  1 , Kosuke Inoue  5   6
Affiliations

Association of Cardiovascular Events With Spouse's Subsequent Dementia

Toshiaki Komura et al. JAMA Neurol. .
No abstract available

Plain language summary

This cohort study evaluates whether a spousal cardiovascular event is associated with one’s own risk of dementia.

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Conflict of interest statement

Conflict of Interest Disclosures: Dr Tsugawa reported receiving funding from the National Institutes of Health (NIH)/National Institute on Aging, the NIH/National Institute on Minority Health and Health Disparities, and Gregory Annenberg Weingarten, GRoW @ Annenberg outside the submitted work; and serving on the board of directors of M3 Inc. Dr Mayeda reported receiving grants from the NIH and grants from California Department of Public Health during the conduct of the study. Dr Glymour reported grants from NIH outside the submitted work. No other disclosures were reported.

Figures

Figure 1.
Figure 1.. Cumulative Incidence Curve for the Matched Index Individuals’ Incidence of Dementia by Spouses’ Cardiovascular Disease (CVD) Event
A cumulative incidence function was applied to account for death of the index individuals.
Figure 2.
Figure 2.. Incidence Rate Ratios (IRRs) of Index Individuals’ Dementia Diagnosis Associated With Spouses’ Cardiovascular Disease (CVD) Events
Each stratum was defined by characteristics of index individuals. The IRRs are computed via multivariable Poisson regression models adjusted for age, age of spouse, sex (not included in male and female), income, index individuals’ history of diabetes (not included in history of diabetes and no history of diabetes), hypertension (not included in history of hypertension and no history of hypertension), and CVD (not included in history of CVD and no history of CVD), as well as spouses’ history of diabetes, hypertension, and dementia.
See this image and copyright information in PMC

References

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