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. 1985 Mar 2;290(6469):663-4.
doi: 10.1136/bmj.290.6469.663.

Hepatitis B virus DNA and e antigen in serum from blood donors in the United Kingdom positive for hepatitis B surface antigen

T J Harrison, V Bal, E G Wheeler, T J Meacock, J F Harrison, A J Zuckerman

Hepatitis B virus DNA and e antigen in serum from blood donors in the United Kingdom positive for hepatitis B surface antigen

T J Harrison et al. Br Med J (Clin Res Ed). .

Abstract

Serum samples from 214 blood donors in the United Kingdom who were carriers of hepatitis B surface antigen (HBsAg) were examined for hepatitis B virus deoxyribonucleic acid (DNA) by DNA:DNA hybridisation and for hepatitis B e antigen (HBeAg) and its antibody. One fifth of the donors carried infectious virus in their circulation. The presence of hepatitis B virus DNA correlated well with that of HBeAg, although hepatitis B virus DNA was found in five serum samples that were negative for HBeAg. It is concluded that analysis of serum samples for hepatitis B virus DNA by hybridisation should be the method of choice for determining whether carriers of HBsAg are infectious.

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References

    1. J Virol. 1973 Nov;12(5):995-1005 - PubMed
    1. N Engl J Med. 1976 Oct 21;295(17):909-13 - PubMed
    1. J Med Virol. 1978;2(1):61-76 - PubMed
    1. J Med Virol. 1978;3(1):59-66 - PubMed
    1. J Clin Pathol. 1980 Nov;33(11):1106-9 - PubMed

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