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Case Reports
. 2024 Jul 26;16(7):e65472.
doi: 10.7759/cureus.65472. eCollection 2024 Jul.

A Case of Primary Hepatic Mucosa-Associated Lymphoid Tissue Lymphoma in a Patient With Primary Biliary Cholangitis and Hashimoto's Thyroiditis

Yunlong Li  1 , Liangrui Zhou  2 , Ning Zhang  3 , Yuchen Wei  1 , Chen Yang  4 , Xiaohong Liu  3 , Lin Kang  3
Affiliations
Case Reports

A Case of Primary Hepatic Mucosa-Associated Lymphoid Tissue Lymphoma in a Patient With Primary Biliary Cholangitis and Hashimoto's Thyroiditis

Yunlong Li et al. Cureus. .

Abstract

Mucosa-associated lymphoid tissue (MALT) lymphoma is a low-grade malignant lymphoproliferative disease, representing a low percentage of newly diagnosed lymphoma cases. Although its exact cause is still unclear, it is commonly associated with infections or autoimmune diseases. The stomach is the most frequent site for MALT lymphoma, with primary hepatic MALT lymphoma being exceptionally rare. Cases of primary hepatic MALT lymphoma often coincide with viral hepatitis. In this report, we present a case of primary hepatic MALT lymphoma in a patient with no history of hepatitis but complicated by primary biliary cholangitis (PBC) and Hashimoto's thyroiditis.

Keywords: hashimoto's thyroiditis; hypothyroidism; management; mucosa-associated lymphoid tissue (malt) lymphoma; primary biliary cholangitis.

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Conflict of interest statement

Human subjects: Consent was obtained or waived by all participants in this study. Conflicts of interest: In compliance with the ICMJE uniform disclosure form, all authors declare the following: Payment/services info: All authors have declared that no financial support was received from any organization for the submitted work. Financial relationships: All authors have declared that they have no financial relationships at present or within the previous three years with any organizations that might have an interest in the submitted work. Other relationships: All authors have declared that there are no other relationships or activities that could appear to have influenced the submitted work.

Figures

Figure 1
Figure 1. 18F-FDG PET/CT imaging identified a 2.5×2.3 cm hyperplastic focus in the right lobe with a SUVmax of 9.3 (arrow)
18F-FDG, 18F-fluorodeoxyglucose; SUVmax, maximum standardized uptake value
Figure 2
Figure 2. Biopsies confirmed the absence of cancer cells in the left lobe cyst but detected lymphocytic infiltration in the right lobe tumor
See this image and copyright information in PMC

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