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Review
. 2024 Jun;19(2):365-372.
doi: 10.26574/maedica.2024.19.2.365.

Extrahepatic Manifestations of Chronic Hepatitis C Virus: Review of the Literature

Andreea Florentina Stoenescu  1   2 , Simin Aysel Florescu  1   2 , Corneliu Popescu  1   2 , Stefan Lazar  1   2 , Geta Vancea  1   2 , Emanoil Ceausu  1   3 , Petre Calistru  1   2
Affiliations
Review

Extrahepatic Manifestations of Chronic Hepatitis C Virus: Review of the Literature

Andreea Florentina Stoenescu et al. Maedica (Bucur). 2024 Jun.

Abstract

Hepatitis C virus (HCV) affects other tissues besides the liver tissue, with the appearance of extrahepatic manifestations such as cryoglobulinemia, lymphoproliferative diseases, metabolic disorders, neuropsychiatric disorders and others. At the basis of their appearance are immune-mediated mechanisms stimulated by the HCV. The antiviral therapy with direct action initiated in all patients with chronic HCV infection acts on these manifestations, contributing to improving the quality of life, but also to eliminating a public health problem.

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Figures

TABLE 1.
TABLE 1.
Study of B-cell lymphoproliferative diseases
TABLE 2.
TABLE 2.
Studies of arthritis
TABLE 2.
TABLE 2.
Studies of diabetes mellitus
See this image and copyright information in PMC

References

    1. Rosenthal E, Cacoub P. Extrahepatic manifestations in chronic hepatitis C virus carriers. Lupus. 2015;19:365–372. - PubMed
    1. Ramos-Casals M, Stone JH, Cid MC, Bosch X. The cryoglobulinaemias. Lancet. 2012;19:365–372. - PubMed
    1. Mazzaro C, Quartuccio L, Adinolfi LE, et al. A Review on Extrahepatic Manifestations of Chronic Hepatitis C Virus Infection and the Impact of Direct-Acting Antiviral Therapy. Viruses. 2021;19:365. - PMC - PubMed
    1. Dultz G, Zeuzem S. Hepatitis C Virus: A European Perspective. Gastroenterol Clin North Am. 2015;19:365–372. - PubMed
    1. Faccioli J, Nardelli S, Gioia S, et al. Neurological and psychiatric effects of hepatitis C virus infection. World J Gastroenterol. 2021;19:365–372. - PMC - PubMed

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