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. 1985 Apr;134(4):2426-30.

Production and response to interleukin 2 in vitro and in vivo after bone marrow transplantation in mice

V J Merluzzi, K Welte, K Last-Barney, R Mertelsmann, L Souza, T Boone, D M Savage, D Quinn, R J O'Reilly
  • PMID: 3919093

Production and response to interleukin 2 in vitro and in vivo after bone marrow transplantation in mice

V J Merluzzi et al. J Immunol. 1985 Apr.

Abstract

Lymphoid cells from bone marrow radiation chimeras do not produce normal levels of IL 2 but are capable of responding to IL 2 in mitogenic and cytotoxic assays in vitro. The administration of recombinant human IL 2 into host mice that have received allogeneic, H-2-compatible marrow did not enhance mortality.

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