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Review
. 2024 Aug 21;30(31):3640-3653.
doi: 10.3748/wjg.v30.i31.3640.

Novel classification of gastric polyps: The good, the bad and the ugly

Deborah Costa  1 , Daryl Ramai  2 , Alberto Tringali  3
Affiliations
Review

Novel classification of gastric polyps: The good, the bad and the ugly

Deborah Costa et al. World J Gastroenterol. .

Abstract

Gastric polyps (GPs) are increasingly common. On upper endoscopy, they should be examined with white light and occasionally chromoendoscopy, and their morphology classified according to the Paris classification. Most GPs have a typical endoscopic appearance and can be associated with diseases like Helicobacter pylori infection. Histological examination is necessary for an accurate diagnosis. While most polyps are non-neoplastic and do not require treatment, some carry a risk of malignancy or are already malignant. Therefore, understanding the diagnosis, classification, and management of GPs is crucial for patient prognostication. Our new classification categorizes GPs into "good", "bad", and "ugly" based on their likelihood of becoming malignant. We aim to provide descriptions of the endoscopic appearance, pathology, treatment, and follow-up for different GPs, as well as clinical management flowcharts.

Keywords: Adenomas; Early gastric cancer; Fundic gland polyps; Gastric polyps; Hyperplastic polyps; Neuroendocrine tumors.

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Conflict of interest statement

Conflict-of-interest statement: All the authors report no relevant conflicts of interest for this article.

Figures

Figure 1
Figure 1
Multiple fundic gland polyps in a patient on proton pump inhibitors.
Figure 2
Figure 2
Antral ectopic pancreas with typical umbilicated shape.
Figure 3
Figure 3
Antral hyperplastic polyps. A: Small sessile; B: Giant polyp.
Figure 4
Figure 4
Antral gastric adenoma.
Figure 5
Figure 5
Small type 1 gastric neuroendocrine tumor.
Figure 6
Figure 6
Early gastric cancer (i-SCAN II, Pentax Medical). A: White light endoscopy; B: Chromoendoscopy.
See this image and copyright information in PMC

References

    1. Park DY, Lauwers GY. Gastric polyps: classification and management. Arch Pathol Lab Med. 2008;132:633–640. - PubMed
    1. Carmack SW, Genta RM, Schuler CM, Saboorian MH. The current spectrum of gastric polyps: a 1-year national study of over 120,000 patients. Am J Gastroenterol. 2009;104:1524–1532. - PubMed
    1. The Paris endoscopic classification of superficial neoplastic lesions: esophagus, stomach, and colon: November 30 to December 1, 2002. Gastrointest Endosc. 2003;58:S3–43. - PubMed
    1. Endoscopic Classification Review Group. Update on the paris classification of superficial neoplastic lesions in the digestive tract. Endoscopy. 2005;37:570–578. - PubMed
    1. Stolte M, Sticht T, Eidt S, Ebert D, Finkenzeller G. Frequency, location, and age and sex distribution of various types of gastric polyp. Endoscopy. 1994;26:659–665. - PubMed

MeSH terms

Supplementary concepts