Restoring PKP2 in arrhythmogenic cardiomyopathy

Silvia G Priori^{1

2

3}

Affiliations

¹ Molecular Cardiology, IRCCS Istituti Clinici Scientifici Maugeri, Pavia, Italy. silvia.priori@icsmaugeri.it.
² Department of Molecular Medicine, University of Pavia, Pavia, Italy. silvia.priori@icsmaugeri.it.
³ Molecular Cardiology, Centro Nacional de Investigaciones Cardiovasculares (CNIC), Madrid, Spain. silvia.priori@icsmaugeri.it.

Comment

Silvia G Priori. Nat Cardiovasc Res. 2023 Dec.

. 2023 Dec;2(12):1115-1116.

doi: 10.1038/s44161-023-00382-z.

Silvia G Priori^{1

2

3}

¹ Molecular Cardiology, IRCCS Istituti Clinici Scientifici Maugeri, Pavia, Italy. silvia.priori@icsmaugeri.it.
² Department of Molecular Medicine, University of Pavia, Pavia, Italy. silvia.priori@icsmaugeri.it.
³ Molecular Cardiology, Centro Nacional de Investigaciones Cardiovasculares (CNIC), Madrid, Spain. silvia.priori@icsmaugeri.it.

No abstract available

Comment on

Therapeutic efficacy of AAV-mediated restoration of PKP2 in arrhythmogenic cardiomyopathy.
Kyriakopoulou E, Versteeg D, de Ruiter H, Perini I, Seibertz F, Döring Y, Zentilin L, Tsui H, van Kampen SJ, Tiburcy M, Meyer T, Voigt N, Tintelen VJP, Zimmermann WH, Giacca M, van Rooij E. Kyriakopoulou E, et al. Nat Cardiovasc Res. 2023;2(12):1262-1276. doi: 10.1038/s44161-023-00378-9. Epub 2023 Dec 7. Nat Cardiovasc Res. 2023. PMID: 38665939 Free PMC article.
Plakophilin 2 gene therapy prevents and rescues arrhythmogenic right ventricular cardiomyopathy in a mouse model harboring patient genetics.
Bradford WH, Zhang J, Gutierrez-Lara EJ, Liang Y, Do A, Wang TM, Nguyen L, Mataraarachchi N, Wang J, Gu Y, McCulloch A, Peterson KL, Sheikh F. Bradford WH, et al. Nat Cardiovasc Res. 2023 Dec;2(12):1246-1261. doi: 10.1038/s44161-023-00370-3. Epub 2023 Dec 7. Nat Cardiovasc Res. 2023. PMID: 39196150 Free PMC article.

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