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Comment
. 2023 Oct;2(10):869-870.
doi: 10.1038/s44161-023-00345-4.

Visualizing inflammatory monocytes and macrophages in the human heart

No authors listed
Comment

Visualizing inflammatory monocytes and macrophages in the human heart

No authors listed. Nat Cardiovasc Res. 2023 Oct.
No abstract available

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Comment on

  • CCR2 Imaging in Human ST-Segment Elevation Myocardial Infarction.
    Lavine KJ, Sultan D, Luehmann H, Detering L, Zhang X, Heo GS, Zhang X, Hoelscher M, Harrison K, Combadière C, Laforest R, Kreisel D, Woodard PK, Brody SL, Gropler RJ, Liu Y. Lavine KJ, et al. Nat Cardiovasc Res. 2023 Oct;2(10):874-880. Epub 2023 Sep 21. Nat Cardiovasc Res. 2023. PMID: 38947883 Free PMC article.

References

    1. Bajpai, G. et al. The human heart contains distinct macrophage subsets with divergent origins and functions. Nat. Med. 24, 1234–1235 (2018). This paper demonstrates the relevance of CCR2+ monocytes and macrophages in the human heart. - DOI - PubMed - PMC
    1. Wienecke, L. M. et al. Imaging targets to visualize the cardiac immune landscape in heart failure. Circ. Cardiovasc. Imaging 16, e014071 (2023). A review article that summarizes immune cells and biomarkers for heart imaging. - DOI - PubMed
    1. Heo, G. S. et al. Molecular imaging visualizes recruitment of inflammatory monocytes and macrophages to the injured heart. Circ. Res. 124, 881–890 (2019). This paper reports the first CCR2 targeted PET imaging of the injured heart. - DOI - PubMed - PMC
    1. Brody, S. L. et al. Chemokine receptor 2-targeted molecular imaging in pulmonary fibrosis. A clinical trial. Am. J. Respir. Crit. Care Med. 203, 78–89 (2021). This paper reports the first investigation of CCR2 imaging in humans. - DOI - PubMed - PMC
    1. Heo, G. S. et al. Nuclear methods for immune cell imaging: bridging molecular imaging and individualized medicine. Circ. Cardiovasc. Imaging 16, e014067 (2023). A review article that summarizes nuclear approaches for immune cell imaging. - DOI - PubMed

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