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. 2024 Aug 28:10.1007/s11764-024-01667-3.
doi: 10.1007/s11764-024-01667-3. Online ahead of print.

Associations between perceived cancer impact and measures of health behavior in survivors of childhood cancer

Megan E Ware  1   2 , Chelsea G Goodenough  3 , Matthew D Wogksch  3 , Kevin R Krull  4   5 , Tara M Brinkman  4 , James R Hebert  6 , Victoria Willard  4 , Rachel Webster  4 , Matthew Ehrhardt  7 , Sedigheh Mirzaei  8 , Gregory T Armstrong  3 , Melissa M Hudson  3 , Kirsten K Ness  3
Affiliations

Associations between perceived cancer impact and measures of health behavior in survivors of childhood cancer

Megan E Ware et al. J Cancer Surviv. .

Abstract

Purpose: Perceived cancer impact (PCI) is the degree to which one feels cancer has impacted one's life. It is unknown if PCI is associated with health behaviors. The aim of this study is to determine associations between PCI and health behaviors in childhood cancer survivors.

Methods: Participants were ≥ 5-year survivors enrolled in the St. Jude Lifetime (SJLIFE) cohort. The Brief Cancer Impact (BCIA) assessed PCI across four domains (caregiving/finances, diet/exercise, social/emotional functioning, religiosity). Responses were categorized as negative, neutral, or positive impact. Smoking, risky drinking, illicit drug use, and diet quality data were obtained via self-report. Physical activity (PA) was assessed via self-report and actigraphy. Cross-sectional and longitudinal associations between PCI and health behaviors were evaluated via multivariable logistic regression.

Results: A total of 3623 participants (mean age 30.4 ± 8.3 years, 49.6% female, 81.5% NH White) were included in baseline cross-sectional analysis; 1709 had a second visit 5.0 ± 1.4 years later and were included in longitudinal analysis. At baseline, the percentage of participants who endorsed cancer as having a negative impact on caregiving/finances was 37.5%, diet/exercise 30.5%, social/emotional functioning 40.6%, and religiosity 8.7%. Negative and neutral PCI across all four domains were cross-sectionally associated with all behaviors except illicit drug use. Negative and neutral PCI at the first time point across all four domains were associated with smoking, diet quality, and PA (ORs ranging from 1.35 to 2.41) in longitudinal analyses.

Conclusions: Endorsing negative or neutral PCI is associated with adverse health behaviors.

Implications for cancer survivors: Promoting optimal health behavior should include addressing PCI.

Keywords: Childhood cancer survivors; Cross-sectional; Health behavior; Longitudinal; Perceived cancer impact.

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Conflict of interest statement

Conflict of Interest Disclosures

Dr. Kirsten Ness is a deputy editor of this journal. Dr. Melissa Hudson is on the editorial board of this journal.

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