Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2024 Nov 1;9(11):957-959.
doi: 10.1001/jamacardio.2024.2654.

Genotype- vs Phenotype-Guided Approaches to Improve ATTR Detection

Affiliations

Genotype- vs Phenotype-Guided Approaches to Improve ATTR Detection

Jessica A Regan et al. JAMA Cardiol. .
No abstract available

PubMed Disclaimer

Comment in

References

    1. Miller DT, Lee K, Chung WK, et al. ; ACMG Secondary Findings Working Group. ACMG SF v3.0 list for reporting of secondary findings in clinical exome and genome sequencing: a policy statement of the American College of Medical Genetics and Genomics (ACMG). Genet Med. 2021;23(8):1381–1390. doi: 10.1038/s41436-021-01172-3 - DOI - PubMed
    1. Damrauer SM, Chaudhary K, Cho JH, et al. Association of the V122I hereditary transthyretin amyloidosis genetic variant with heart failure among individuals of African or Hispanic/Latino ancestry. JAMA. 2019;322(22):2191–2202. doi: 10.1001/jama.2019.17935 - DOI - PMC - PubMed
    1. Maurer MS, Hanna M, Grogan M, et al. ; THAOS Investigators. Genotype and phenotype of transthyretin cardiac amyloidosis: THAOS (Transthyretin Amyloid Outcome Survey). J Am Coll Cardiol. 2016;68(2):161–172. doi: 10.1016/j.jacc.2016.03.596 - DOI - PMC - PubMed
    1. Aimo A, Castiglione V, Rapezzi C, et al. RNA-targeting and gene editing therapies for transthyretin amyloidosis. Nat Rev Cardiol. 2022;19 (10):655–667. doi: 10.1038/s41569-022-00683-z - DOI - PubMed
    1. Aung N, Nicholls HL, Chahal CAA, et al. Prevalence, cardiac phenotype, and outcomes of transthyretin variants in the UK Biobank population. JAMA Cardiol. Published online August 28, 2024. doi: 10.1001/jamacardio.2024.2190 - DOI - PMC - PubMed