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Review
. 2024 Aug 21;13(16):4926.
doi: 10.3390/jcm13164926.

From Diagnosis to Fertility: Optimizing Treatment of Adenomyosis for Reproductive Health

Hanna Kim  1 , Emily H Frisch  1 , Tommaso Falcone  1
Affiliations
Review

From Diagnosis to Fertility: Optimizing Treatment of Adenomyosis for Reproductive Health

Hanna Kim et al. J Clin Med. .

Abstract

Adenomyosis is a benign gynecologic disorder that had previously not been well studied or understood. However, it is now become a more common diagnosis with long-standing implications especially for fertility. In this literature review, the pathophysiology and diagnosis along with management options for uterine preservation and fertility along with more definitive options are reviewed. While there is a better understanding of adenomyosis, there is still more research that is needed to fully elucidate the best ways of management for patients especially in those seeking fertility.

Keywords: adenomyosis; fertility preservation; surgical management options.

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Conflict of interest statement

The authors declare no conflicts of interest.

Figures

Figure 1
Figure 1
MRI image showing diffuse adenomyosis.
See this image and copyright information in PMC

References

    1. Benagiano G., Brosens I. History of Adenomyosis. Best Pract. Res. Clin. Obstet. Gynaecol. 2006;20:449–463. doi: 10.1016/j.bpobgyn.2006.01.007. - DOI - PubMed
    1. Younes G., Tulandi T. Conservative Surgery for Adenomyosis and Results: A Systematic Review. J. Minim. Invasive Gynecol. 2018;25:265–276. doi: 10.1016/j.jmig.2017.07.014. - DOI - PubMed
    1. Park C.W., Choi M.H., Yang K.M., Song I.O. Pregnancy Rate in Women with Adenomyosis Undergoing Fresh or Frozen Embryo Transfer Cycles Following Gonadotropin-Releasing Hormone Agonist Treatment. Clin. Exp. Reprod. Med. 2016;43:169–173. doi: 10.5653/cerm.2016.43.3.169. - DOI - PMC - PubMed
    1. Vannuccini S., Tosti C., Carmona F., Huang S.J., Chapron C., Guo S.-W., Petraglia F. Pathogenesis of Adenomyosis: An Update on Molecular Mechanisms. Reprod. Biomed. Online. 2017;35:592–601. doi: 10.1016/j.rbmo.2017.06.016. - DOI - PubMed
    1. Vannuccini S., Petraglia F. Recent Advances in Understanding and Managing Adenomyosis. F1000Research. 2019;8:283. doi: 10.12688/f1000research.17242.1. - DOI - PMC - PubMed

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