Retraction: Chitinase 1 regulates pulmonary fibrosis by modulating TGF-β/SMAD7 pathway via TGFBRAP1 and FOXO3

Chang-Min Lee¹, Chuan-Hua He¹, Jin Wook Park¹, Jae Hyun Lee², Suchitra Kamle¹, Bing Ma¹, Bedia Akosman¹, Roberto Cortez¹, Emily Chen¹, Yang Zhou¹, Erica L Herzog³, Changwan Ryu², Xueyan Peng², Ivan O Rosas⁴, Sergio Poli⁴, Carol Feghali Bostwick⁵, Augustine M Choi⁶, Jack A Elias^{1

7}, Chun Geun Lee⁸

Affiliations

¹ Molecular Microbiology and Immunology, Brown University, Providence, RI, USA.
² Department of Internal Medicine, Yonsei University College of Medicine, Seoul, South Korea.
³ Section of Pulmonary, Critical Care, and Sleep Medicine, Department of Internal Medicine, Yale School of Medicine, New Haven, CT, USA.
⁴ Brigham and Women's Hospital, Boston, MA, USA.
⁵ Department of Medicine, College of Medicine, Medical University of South Carolina, Charleston, SC, USA.
⁶ Weill Cornell Medicine Pulmonary and Critical Care Medicine, New York, NY, USA.
⁷ Division of Medicine and Biological Sciences, Brown University, Warren Alpert School of Medicine, Providence, RI, USA.
⁸ Molecular Microbiology and Immunology, Brown University, Providence, RI, USA chun_lee@brown.edu.

PMID: 39209538
PMCID: PMC11361373
DOI: 10.26508/lsa.202402987

Retraction: Chitinase 1 regulates pulmonary fibrosis by modulating TGF-β/SMAD7 pathway via TGFBRAP1 and FOXO3

Chang-Min Lee et al. Life Sci Alliance. 2024.

. 2024 Aug 29;7(11):e202402987.

doi: 10.26508/lsa.202402987. Print 2024 Nov.

Authors

Affiliations

¹ Molecular Microbiology and Immunology, Brown University, Providence, RI, USA.
² Department of Internal Medicine, Yonsei University College of Medicine, Seoul, South Korea.
³ Section of Pulmonary, Critical Care, and Sleep Medicine, Department of Internal Medicine, Yale School of Medicine, New Haven, CT, USA.
⁴ Brigham and Women's Hospital, Boston, MA, USA.
⁵ Department of Medicine, College of Medicine, Medical University of South Carolina, Charleston, SC, USA.
⁶ Weill Cornell Medicine Pulmonary and Critical Care Medicine, New York, NY, USA.
⁷ Division of Medicine and Biological Sciences, Brown University, Warren Alpert School of Medicine, Providence, RI, USA.
⁸ Molecular Microbiology and Immunology, Brown University, Providence, RI, USA chun_lee@brown.edu.

PMID: 39209538
PMCID: PMC11361373
DOI: 10.26508/lsa.202402987

Abstract

Chitinase 1 (CHIT1) plays a role in the pathogenesis of pulmonary fibrosis by modulating canonical and noncanonical TGF-β signaling via interaction with TGFBRAP1 and FOXO3. These findings highlight the CHIT1/SMAD7 axis as a potential biomarker and therapeutic target of pulmonary fibrosis.

PubMed Disclaimer

Retraction of

Chitinase 1 regulates pulmonary fibrosis by modulating TGF-β/SMAD7 pathway via TGFBRAP1 and FOXO3.
Lee CM, He CH, Park JW, Lee JH, Kamle S, Ma B, Akosman B, Cotez R, Chen E, Zhou Y, Herzog EL, Ryu C, Peng X, Rosas IO, Poli S, Bostwick CF, Choi AM, Elias JA, Lee CG. Lee CM, et al. Life Sci Alliance. 2019 May 13;2(3):e201900350. doi: 10.26508/lsa.201900350. Print 2019 Jun. Life Sci Alliance. 2019. Retraction in: Life Sci Alliance. 2024 Aug 29;7(11):e202402987. doi: 10.26508/lsa.202402987. PMID: 31085559 Free PMC article. Retracted.

Publication types

Actions

LinkOut - more resources

Full Text Sources
- HighWire
- PubMed Central
Miscellaneous
- NCI CPTAC Assay Portal

Save citation to file

Email citation

Add to Collections

Add to My Bibliography

Your saved search

Create a file for external citation management software

Your RSS Feed

Retraction: Chitinase 1 regulates pulmonary fibrosis by modulating TGF-β/SMAD7 pathway via TGFBRAP1 and FOXO3

Affiliations

Retraction: Chitinase 1 regulates pulmonary fibrosis by modulating TGF-β/SMAD7 pathway via TGFBRAP1 and FOXO3

Authors

Affiliations

Abstract

Retraction of

Publication types

LinkOut - more resources

Full Text Sources

Miscellaneous