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. 1985 Jan;27(1):76-8.
doi: 10.1128/AAC.27.1.76.

Activities of new quinoline derivatives against genital pathogens

J Aznar, M C Caballero, M C Lozano, C de Miguel, J C Palomares, E J Perea

Activities of new quinoline derivatives against genital pathogens

J Aznar et al. Antimicrob Agents Chemother. 1985 Jan.

Abstract

The in vitro activities of four quinoline carboxylic acids against 48 strains of Neisseria gonorrhoeae, 10 of Chlamydia trachomatis, and 32 of Ureaplasma urealyticum were compared. Ciprofloxacin was the most active against N. gonorrhoeae and C. trachomatis but had poor bactericidal activity against U. urealyticum, whereas ofloxacin showed the most bactericidal activity against U. urealyticum but was less active than ciprofloxacin against the two former pathogens. Norfloxacin and enoxacin were less active against all the studied pathogens.

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