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. 2024 Nov 27;13(11):585-588.
doi: 10.1093/jpids/piae085.

Evaluation of Transplacental Maternal SARS-CoV-2 Antibody Transfer in Small for Gestational Age Infants

Alisa Kachikis  1 , Mindy Pike  1 , Linda O Eckert  1   2 , Emma A Roberts  3 , Alexis Baranoff  4 , Sharon Kung  1 , Erin A Goecker  5 , Michael G Gravett  1   2 , Alexander L Greninger  5 , Janet A Englund  6
Affiliations

Evaluation of Transplacental Maternal SARS-CoV-2 Antibody Transfer in Small for Gestational Age Infants

Alisa Kachikis et al. J Pediatric Infect Dis Soc. .

Abstract

Little is known about the potential benefits of maternal immunization in the setting of high-risk pregnancies resulting in small-for-gestational-age (SGA) infants. This study compares transplacental transfer of maternal SARS-CoV-2 anti-Spike antibody in pregnancies with SGA compared to appropriate-for-gestational-age infants.

Keywords: SARS-CoV-2; maternal immunization; small-for-gestational-age infant; transplacental antibody transfer; vaccination in pregnancy.

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Figures

Figure 1.
Figure 1.
a. Boxplot showing the overall distribution of anti-S antibody by birthweight criteria for the entire cohort. b. Boxplot showing the distribution of anti-S antibody by birthweight criteria in participants with hybrid immunity (prior infection or anti-N+). Boxplot showing the distribution of anti-S antibody by birthweight criteria in participants with vaccine-mediated immunity (no prior infection and anti-N−).
See this image and copyright information in PMC

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