doi: 10.1007/BF00268283.
Genetical and cytological location of the structural parts coding for the first three steps of pyrimidine biosynthesis in Drosophila melanogaster
- PMID: 39220
- DOI: 10.1007/BF00268283
Item in Clipboard
Genetical and cytological location of the structural parts coding for the first three steps of pyrimidine biosynthesis in Drosophila melanogaster
Mol Gen Genet.
.
Abstract
The rudimentary locus (r; X--55.3) of Drosophila melanogaster is shown to contain the structural sequences for the enzymes CPSase, ATCase and DHOase. The enzyme concentration in adult flies is correlated with the number of r+ copies in the genome. The expression of the locus follows the rules of the gene dosage compensation hypothesis when extracts of newly emerged males and females are compared.
Similar articles
-
Genetic and biochemical properties of revertants at the rudimentary locus in Drosophila melanogaster.Mol Gen Genet. 1981;183(2):270-6. doi: 10.1007/BF00270628. Mol Gen Genet. 1981. PMID: 6120439
-
Rudimentary locus of Drosophila melanogaster: partial purification of a carbamylphosphate synthase--aspartate transcarbamylase--dihydroorotase complex.Biochem Genet. 1978 Apr;16(3-4):321-32. doi: 10.1007/BF00484088. Biochem Genet. 1978. PMID: 28118
-
Structural and transcriptional analysis of the pyrABCN, pyrD and pyrF genes in Aspergillus nidulans and the evolutionary origin of fungal dihydroorotases.Mol Microbiol. 1999 Aug;33(3):599-611. doi: 10.1046/j.1365-2958.1999.01507.x. Mol Microbiol. 1999. PMID: 10417650
-
The evolutionary history of the first three enzymes in pyrimidine biosynthesis.Bioessays. 1993 Mar;15(3):157-64. doi: 10.1002/bies.950150303. Bioessays. 1993. PMID: 8098212 Review.
-
[The pyrimidine-biosynthetic (pyr) gene cluster in trypanosomes].Tanpakushitsu Kakusan Koso. 2002 Jan;47(1):13-20. Tanpakushitsu Kakusan Koso. 2002. PMID: 11808190 Review. Japanese. No abstract available.
Cited by
-
Organization of transcription units around the Drosophila melanogaster rudimentary locus and temporal pattern of expression.Mol Gen Genet. 1986 Mar;202(3):493-9. doi: 10.1007/BF00333283. Mol Gen Genet. 1986. PMID: 3012273
-
Molecular characterization of the 5' end of the rudimentary gene in Drosophila and analysis of three P element insertions.Nucleic Acids Res. 1992 Sep 11;20(17):4639-47. doi: 10.1093/nar/20.17.4639. Nucleic Acids Res. 1992. PMID: 1329025 Free PMC article.
-
Genetic and biochemical properties of revertants at the rudimentary locus in Drosophila melanogaster.Mol Gen Genet. 1981;183(2):270-6. doi: 10.1007/BF00270628. Mol Gen Genet. 1981. PMID: 6120439
-
Cytogenetic analysis of the 2B3-4--2B11 region of the X-chromosome of Drosophila melanogaster. I. Cytology of the region and mutant complementation groups.Chromosoma. 1980;81(2):281-306. doi: 10.1007/BF00285954. Chromosoma. 1980. PMID: 6777125
-
Rudimentary mutants ofDrosophila melanogaster : Isolation and characterization of pyrimidine auxotrophic cell lines.Wilehm Roux Arch Dev Biol. 1979 Jun;187(2):167-177. doi: 10.1007/BF00848269. Wilehm Roux Arch Dev Biol. 1979. PMID: 28304928
