Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2024 Aug 16:4:1441343.
doi: 10.3389/fopht.2024.1441343. eCollection 2024.

Evaluation of agreement of IOP measurements by Tono-Vera tonometer to Goldmann applanation tonometry

Charles R Niles  1 , Alexander R Crinzi  2 , Russell Bonaventura  3 , David A Taylor  3
Affiliations

Evaluation of agreement of IOP measurements by Tono-Vera tonometer to Goldmann applanation tonometry

Charles R Niles et al. Front Ophthalmol (Lausanne). .

Abstract

Purpose: To evaluate the accuracy of the new Tono-Vera rebound tonometer (Reichert Inc, Buffalo, NY) compared to Goldmann Applanation Tonometry.

Methods: This prospective, observational, cross-sectional study was designed in accordance with ANSI Z80.10-2014 and ISO 8612-2009 guidelines for tonometer comparison. Intraocular Pressure (IOP) was measured by Goldmann Applanation and Tono-Vera on 160 eyes of 160 subjects. Corneal Astigmatism and Central Corneal Thickness were also measured. A single investigator (CN) conducted all measurements. The average of two measurements from each tonometer was used in the analysis. Bland-Altman plots, total least squares regression analysis, and simple linear regression were used to evaluate agreement between the tonometers.

Results: Average IOP values from Goldmann Applanation and Tono-Vera were not significantly different (19.17 and 19.03 respectively, p=0.40, paired t-test). The total least squares regression analysis indicated strong agreement between the two tonometers (slope +0.97, offset +0.49 mmHg, standard deviation 2.11 mmHg). There were 2 IOP measurement pairs that exceeded the ± 5 mmHg limits of agreement required in ANSI Z80.10-2014 and ISO 8612-2009, which is within the range of acceptability specified in the standards.

Conclusion: We evaluated IOP measurements by Tono-Vera Rebound Tonometer vs Goldmann Applanation Tonometry for eyes with a wide range of IOP values and found no statistically significant differences in the results. Tono-Vera meets the requirements of ANSI Z80.10-2014 and ISO 8612-2009, demonstrating accuracy comparable to Goldmann tonometry.

Keywords: GAT; Goldmann; IOP; Rebound; Tono-Vera; tonometer; tonometry.

PubMed Disclaimer

Conflict of interest statement

Authors DT and RB were employed by the company Reichert, Inc. Authors AC and CN have received consulting payments from Reichert. The authors declare that the study received funding from Reichert Inc. Reichert Inc. was involved in the design, analysis, and interpretation of the data, the writing of the article, and the decision to submit it for publication.

Figures

Figure 1
Figure 1
Total Least Squares Regression of Tono-Vera vs GAT for all 160 eyes.
Figure 2
Figure 2
Total Least Squares Regression of Tono-Vera vs GAT for 137 low corneal astigmatism eyes.
Figure 3
Figure 3
Total Least Squares Regression of Tono-Vera vs GAT for high corneal astigmatism eyes.
Figure 4
Figure 4
Bland-Altman Comparison of Tono-Vera to GAT for all 160 eyes.
Figure 5
Figure 5
Bland-Altman Comparison of Tono-Vera to GAT for 137 low corneal astigmatism eyes.
Figure 6
Figure 6
Bland-Altman Comparison of Tono-Vera to GAT for high corneal astigmatism eyes.
Figure 7
Figure 7
Scatter Plot of GAT & Tono-Vera vs CCT for all 160 eyes.
See this image and copyright information in PMC

References

    1. Tham YC, Li X, Wong TY, Quigley HA, Aung T, Cheng CY. Global prevalence of glaucoma and projections of glaucoma burden through 2040: a systematic review and meta-analysis. Ophthalmology. (2014) 121:2081–90. doi: 10.1016/j.ophtha.2014.05.013 - DOI - PubMed
    1. Kass MA, Heuer DK, Higginbotham EJ, Johnson CA, Keltner JL, Miller JP, et al. . The Ocular Hypertension Treatment Study: a randomized trial determines that topical ocular hypotensive medication delays or prevents the onset of primary open-angle glaucoma. Arch Ophthalmol. (2002) 120:701–13. discussion 829–830. doi: 10.1001/archopht.120.6.701 - DOI - PubMed
    1. Leske MC, Heijl A, Hussein M, Bengtsson B, Hyman L, Komaroff E, et al. . Factors for glaucoma progression and the effect of treatment: the early manifest glaucoma trial. Arch Ophthalmol. (2003) 121:48–56. doi: 10.1001/archopht.121.1.48 - DOI - PubMed
    1. The Advanced Glaucoma Intervention Study (AGIS) 7. The relationship between control of intraocular pressure and visual field deterioration. The AGIS Investigators. Am J Ophthalmol. (2000) 130:429–40. doi: 10.1016/S0002-9394(00)00538-9 - DOI - PubMed
    1. Collaborative Normal-Tension Glaucoma Study Group . Comparison of glaucomatous progression between untreated patients with normal-tension glaucoma and patients with therapeutically reduced intraocular pressures. Am J Ophthalmol. (1998) 126:487–97. doi: 10.1016/S0002-9394(98)00223-2 - DOI - PubMed

LinkOut - more resources