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Case Reports
. 2024 Aug 27;20(1):70-73.
doi: 10.14797/mdcvj.1395. eCollection 2024.

Unusual Evidence of Fat Embolism in the Subclavian Vein Detected by High-Intensity Transient Signals

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Case Reports

Unusual Evidence of Fat Embolism in the Subclavian Vein Detected by High-Intensity Transient Signals

Valeria Ortega et al. Methodist Debakey Cardiovasc J. .

Abstract

Fat emboli may occur in patients after traumatic fractures or orthopedic procedures; however, their clinical detection is a very rare finding. Here, we describe a 77-year-old female who was admitted to the emergency department with a fracture of the right humerus. We diagnosed fat embolism after an ultrasound of the right subclavian vein. The embolism was detected by high-intensity transient signals present on the spectral Doppler. While these signals are well known for microembolization in transcranial Doppler, to our knowledge this is the first case report in the medical literature to observe and describe high-intensity transient signals seen in the upper extremities by spectral Doppler. Although it is unusual to detect a fat embolism in transit, we believe clinicians should be aware of this finding, particularly when evaluating high-risk patients.

Keywords: fat embolism; fat embolism syndrome; high-intensity transient signals; spectral Doppler; subclavian vein; venous duplex ultrasound.

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Conflict of interest statement

The authors have no competing interests to declare.

Figures

Venous duplex ultrasound of the right subclavian vein
Figure 1
Venous duplex ultrasound of the right subclavian vein. (A) The rhomboid box illustrates the color Doppler showing blue blood flow without any visible clot. (B) Spectral Doppler (Zoom) shows multiple high intensity transient signals representing fat microemboli (denoted by yellow arrows).
Venous duplex ultrasound of the left subclavian vein
Figure 2
Venous duplex ultrasound of the left subclavian vein. Doppler image demonstrates normal blood flow and no detection of high intensity transient signals in the spectral Doppler.

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References

    1. Von Bergmann E. Ein fall todlicher fettenbolic. Berl Klin Wochenscher 1873;10:385.
    1. Saleh M, Juan E. Cerebral fat emboli syndrome: do not miss the transcranial Doppler findings. BMJ Case Rep. 2015. May 6;2015:bcr2015210445. doi: - PMC - PubMed
    1. Herndon JH, Bechtol CO, Crickenberger DP. Fat embolism during total hip replacement. A prospective study. J Bone Joint Surg Am. 1974. Oct;56(7):1350–62. PMID: 4447670 - PubMed
    1. Husebye EE, Lyberg T, Røise O. Bone marrow fat in the circulation: clinical entities and pathophysiological mechanisms. Injury. 2006. Oct;37 Suppl 4:S8–18. doi: - PubMed
    1. Jorgensen A, Bashir A, Satpathy J. Cerebral fat embolism syndrome (FES): similar cases with different outcomes. BMJ Case Rep. 2018. Oct 8;2018:bcr2018225261. doi: - PMC - PubMed

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