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Review
. 2024 Aug 28;30(32):3739-3742.
doi: 10.3748/wjg.v30.i32.3739.

Radical cholecystectomy without liver resection for peritoneal side early incidental gallbladder cancer

Gaetano Piccolo  1 , Matteo Barabino  2 , Guglielmo Niccolò Piozzi  3 , Paolo Pietro Bianchi  2
Affiliations
Review

Radical cholecystectomy without liver resection for peritoneal side early incidental gallbladder cancer

Gaetano Piccolo et al. World J Gastroenterol. .

Abstract

Gallbladder cancer (GBC) is a rare disease with a poor prognosis. Simple cholecystectomy may be an adequate treatment only for very early disease (Tis, T1a), whereas reoperation is recommended for more advanced disease (T1b and T2). Radical cholecystectomy should have two fundamental objectives: To radically resect the liver parenchyma and to achieve adequate clearance of the lymph nodes. However, recent studies have shown that compared with lymph node dissection alone, liver resection does not improve survival outcomes. The oncological roles of lymphadenectomy and liver resection is distinct. Therefore, for patients with incidental GBC without liver invasion, hepatic resection is not always mandatory.

Keywords: Early stage; Incidental gallbladder cancer; Liver resection; Radical cholecystectomy; Reoperation.

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Conflict of interest statement

Conflict-of-interest statement: The corresponding author declares that the manuscript has been submitted on behalf of all authors. All authors declare that they have no competing interests.

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