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. 2024 Sep 2;120(10):e41-e43.
doi: 10.1093/cvr/cvae140.

Zilebesiran, a ribonucleic acid interference agent targeting angiotensinogen, proves a promising approach in hypertension

David J Webb  1
Affiliations

Zilebesiran, a ribonucleic acid interference agent targeting angiotensinogen, proves a promising approach in hypertension

David J Webb. Cardiovasc Res. .
No abstract available

Keywords: Angiotensinogen; Gene silencing; Hypertension; Medication adherence; RNA interference.

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Conflict of interest statement

Conflict of interest: Professor Webb’s employer, the University of Edinburgh, has been paid by Alnylam for his contributions to the zilebesiran programme in hypertension. He has undertaken recent consultancy roles with Idorsia, Janssen, and Silence pharmaceuticals in the field of cardiovascular research.