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Review
. 2024 Feb 29;74(740):134-136.
doi: 10.3399/bjgp24X736665. Print 2024 Mar.

Faecal calprotectin in primary care: is its current use supported by the evidence?

Robert W Perry  1 , David Mummery  2 , James L Alexander  1 , Lucy C Hicks  1 , Horace RT Williams  1
Affiliations
Review

Faecal calprotectin in primary care: is its current use supported by the evidence?

Robert W Perry et al. Br J Gen Pract. .
No abstract available

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Conflict of interest statement

The authors have declared no competing interests.

Figures

Figure 1.
Figure 1.
Proposed flowchart for FC testing in primary care based on existing guidelines.,,, aExact thresholds to be determined locally and dependent on FC assay used. FC = faecal calprotectin. IBS = irritable bowel syndrome. NICE = National Institute for Health and Care Excellence.
See this image and copyright information in PMC

References

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    1. Turner D, Ricciuto A, Lewis A, et al. STRIDE-II: an update on the Selecting Therapeutic Targets in Inflammatory Bowel Disease (STRIDE) initiative of the International Organization for the Study of IBD (IOIBD): determining therapeutic goals for treat-to-target strategies in IBD. Gastroenterology. 2021;160(5):1570–1583. - PubMed
    1. Freeman K, Taylor-Phillips S, Willis BH, et al. Test accuracy of faecal calprotectin for inflammatory bowel disease in UK primary care: a retrospective cohort study of the IMRD-UK data. BMJ Open. 2021;11(2):e044177. - PMC - PubMed
    1. Conroy S, Hale MF, Cross SS, et al. Unrestricted faecal calprotectin testing performs poorly in the diagnosis of inflammatory bowel disease in patients in primary care. J Clin Pathol. 2018;71(4):316–322. - PubMed
    1. National Institute for Health and Care Excellence (NICE) Faecal calprotectin diagnostic tests for inflammatory diseases of the bowel. DG11. London: NICE; 2013. https://www.nice.org.uk/guidance/dg11 (accessed 6 Feb 2024).

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