Inhibition of phagosome-lysosome fusion in macrophages by soluble extracts of virulent Brucella abortus
- PMID: 3922258
Inhibition of phagosome-lysosome fusion in macrophages by soluble extracts of virulent Brucella abortus
Abstract
Water extracts of virulent Brucella abortus were able to inhibit phagosome-lysosome fusion in unelicited murine peritoneal macrophages following ingestion of yeast. Extracts from an avirulent strain were unable to produce a similar effect. Lipopolysaccharide from B abortus did not appear to be involved with the ability of the extracts to inhibit fusion.
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