This is a preprint.
Staphylococcus aureus Tetracycline Resistance and Co-resistance in a Doxy-PEP-Eligible Population
- PMID: 39228717
- PMCID: PMC11370501
- DOI: 10.1101/2024.08.22.24312434
Staphylococcus aureus Tetracycline Resistance and Co-resistance in a Doxy-PEP-Eligible Population
Update in
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Staphylococcus aureus Tetracycline Resistance and Co-resistance in a Doxycycline Postexposure Prophylaxis-Eligible Population.J Infect Dis. 2025 Apr 15;231(4):e708-e712. doi: 10.1093/infdis/jiae634. J Infect Dis. 2025. PMID: 39718967 Free PMC article.
Abstract
In Staphylococcus aureus infections in men eligible for doxycycline post-exposure prophylaxis (doxy-PEP), tetracycline non-susceptibility is more prevalent than in the overall population and is associated with resistance to trimethoprim-sulfamethoxazole and clindamycin. Doxy-PEP may select for S. aureus multi-drug resistance, underscoring the importance of surveillance.
References
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- Centers for Disease Control and Prevention. Sexually Transmitted Disease Surveillance 2022. Atlanta: U.S. Department of Health and Human Services; 2024.
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