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Case Reports
. 2025 Jan;56(1):54-56.
doi: 10.3928/23258160-20240729-01. Epub 2024 Aug 1.

Macular Hole Self Closure While Awaiting Pre-operative Clearance

Free article
Case Reports

Macular Hole Self Closure While Awaiting Pre-operative Clearance

Michael Javaheri et al. Ophthalmic Surg Lasers Imaging Retina. 2025 Jan.
Free article

Abstract

A 69-year-old white woman with a history of vitreomacular traction (VMT) presented with a 2-week history of visual loss in the right eye. Visual acuity, with correction, measured 20/200 in the right eye. Examination revealed a partial posterior vitreous detachment and a stage 2 full-thickness macular hole (FTMH). Spectral-domain optical coherence tomography (SD-OCT) testing confirmed a stage 2 FTMH with VMT. Pars plana vitrectomy without internal limiting membrane peeling was planned and the patient was sent for preoperative clearance, where she was diagnosed with atrial fibrillation and wanted to delay surgery. Two months later, the patient returned for follow-up with a visual acuity of 20/80, a closed macular hole, and an incomplete posterior vitreous detachment in her right eye. Four months later, the patient exhibited a completely closed FTMH with a visual acuity of 20/30. Spontaneous resolution of FTMHs (stages 2 to 4) in the adult population is an extremely rare event, occurring in less than 4% of affected eyes. We describe a patient with a stage 2 FTMH who exhibited spontaneous resolution due to the resolution of VMT while awaiting preoperative clearance. [Ophthalmic Surg Lasers Imaging Retina 2025;56:54-56.].

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Conflict of interest statement

Disclosure: MJ is a consultant for Regeneron and Genentech; a speaker for Regeneron and Genentech; on an advisory board for Regeneron, Genentech, and Apellis; the treasurer of the Los Angeles Society of Ophthalmology; and on the executive board of The Masket Foundation. PSP is a consultant for Alimera Sciences; a speaker for Regeneron, Dutch Ophthalmic Research Center (DORC) USA, and OD-OS GmbH; and has received payment for expert testimony from Pro/Consul. The remaining author has disclosed no potential conflicts of interest, financial or otherwise.

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