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Comment
. 2024 Sep;47(9):2574-2576.
doi: 10.1038/s41440-024-01802-8. Epub 2024 Jul 11.

Will esaxerenone be added to the antihypertensive treatment strategy of practicing physicians as a second-line antihypertensive drug?

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Comment

Will esaxerenone be added to the antihypertensive treatment strategy of practicing physicians as a second-line antihypertensive drug?

Tetsuro Yoshida. Hypertens Res. 2024 Sep.
No abstract available

Keywords: Esaxerenone; Mineralocorticoid receptor antagonists; Trichlormethiazide.

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References

    1. Ito S, Itoh H, Rakugi H, Okuda Y, Yoshimura M, Yamakawa S. Double-blind randomized phase 3 study comparing esaxerenone (CS-3150) and Eplerenone in Patients With Essential Hypertension (ESAX-HTN Study). Hypertension. 2020;75:51–8. - DOI - PubMed
    1. Kario K, Ohbayashi H, Hashimot M, Itabashi N, Kato M, Uchiyama K, et al. Home blood pressure-lowering effect of a non-steroidal mineralocorticoid receptor blocker, esaxerenone, versus thichlormethiazide for uncontrolled hypertension: the EXCITE-HT randomized controlled study. Hypertens Res. https://doi.org/10.1038/s41440-024-01762-z .
    1. Kario K, Wang JG, Chia YC, Wang TD, Li Y, Siddique S, et al. The HOPE Asia network 2022 up-date consensus statement on morning hypertension management. J Clin Hypertens. 2022;24:1112–20. - DOI
    1. Kario K, Nishizawa M, Kato M, Ishii H, Uchiyama K, Nagai M, et al. Nighttime home blood pressure lowering effect of esaxerenone in patients with uncontrolled nocturnal hypertension: the EARLY-NH study. Hypertens Res. 2023;46:1782–94. - DOI - PubMed - PMC
    1. Yamamoto E, Usuku H, Sueta D, Suzuki S, Nakamura T, Matsui K, et al. Efficacy and Safety of Esaxerenone in Hypertensive Patients with Left Ventricular Hypertrophy (ESES-LVH) Study: a multicenter, open-label, prospective, interventional study. Adv Ther. 2024;41:1284–303. - DOI - PubMed - PMC

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