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. 2024 Sep 4;7(3):ooae081.
doi: 10.1093/jamiaopen/ooae081. eCollection 2024 Oct.

Bridging clinical informatics and implementation science to improve cancer symptom management in ambulatory oncology practices: experiences from the IMPACT consortium

Nadine Jackson McCleary  1 , James L Merle  2 , Joshua E Richardson  3 , Michael Bass  4 , Sofia F Garcia  4 , Andrea L Cheville  5 , Sandra A Mitchell  6 , Roxanne Jensen  6 , Sarah Minteer  5 , Jessica D Austin  7 , Nathan Tesch  8 , Lisa DiMartino  9   10 , Michael J Hassett  1 , Raymond U Osarogiagbon  11 , Sandra Wong  12 , Deborah Schrag  13 , David Cella  14 , Ashley Wilder Smith  6 , Justin D Smith  2 ; IMPACT Consortium
Collaborators, Affiliations

Bridging clinical informatics and implementation science to improve cancer symptom management in ambulatory oncology practices: experiences from the IMPACT consortium

Nadine Jackson McCleary et al. JAMIA Open. .

Abstract

Objectives: To report lessons from integrating the methods and perspectives of clinical informatics (CI) and implementation science (IS) in the context of Improving the Management of symPtoms during and following Cancer Treatment (IMPACT) Consortium pragmatic trials.

Materials and methods: IMPACT informaticists, trialists, and implementation scientists met to identify challenges and solutions by examining robust case examples from 3 Research Centers that are deploying systematic symptom assessment and management interventions via electronic health records (EHRs). Investigators discussed data collection and CI challenges, implementation strategies, and lessons learned.

Results: CI implementation strategies and EHRs systems were utilized to collect and act upon symptoms and impairments in functioning via electronic patient-reported outcomes (ePRO) captured in ambulatory oncology settings. Limited EHR functionality and data collection capabilities constrained the ability to address IS questions. Collecting ePRO data required significant planning and organizational champions adept at navigating ambiguity.

Discussion: Bringing together CI and IS perspectives offers critical opportunities for monitoring and managing cancer symptoms via ePROs. Discussions between CI and IS researchers identified and addressed gaps between applied informatics implementation and theory-based IS trial and evaluation methods. The use of common terminology may foster shared mental models between CI and IS communities to enhance EHR design to more effectively facilitate ePRO implementation and clinical responses.

Conclusion: Implementation of ePROs in ambulatory oncology clinics benefits from common understanding of the concepts, lexicon, and incentives between CI implementers and IS researchers to facilitate and measure the results of implementation efforts.

Keywords: cancer; electronic health information; implementation science; medical information; patient-reported outcomes; symptom management.

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Conflict of interest statement

The authors have no competing interests to report.

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