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Review
. 2024 Nov-Dec;41(6):1021-1029.
doi: 10.1111/pde.15687. Epub 2024 Sep 5.

How many is too many? A review of the significant numbers in pediatric skin lesions and their recommended evaluation

Carly Mulinda  1 , Sonora Yun  1 , Justine Fenner  2 , Maria C Garzon  3   4 , Margaret E Scollan  1 , Laura E Levin  3
Affiliations
Review

How many is too many? A review of the significant numbers in pediatric skin lesions and their recommended evaluation

Carly Mulinda et al. Pediatr Dermatol. 2024 Nov-Dec.

Abstract

Pediatric dermatologists are frequently consulted to evaluate children for cutaneous signs of systemic disorders. Numerical thresholds of significance have been described in the dermatologic literature for various skin findings where the likelihood of an associated extracutaneous abnormality or known genetic syndrome increases significantly. Knowledge of these numerical thresholds facilitates diagnosis and management, which improves clinical outcomes and avoids severe complications. This review highlights the clinical presentation, complications, evaluation, and numerical significance, when applicable, for the following skin findings: infantile hemangiomas, capillary malformations, café-au-lait macules, hypopigmented macules, juvenile xanthogranulomas, pilomatricomas, and angiofibromas.

Keywords: infantile hemangiomas; multiple abnormalities; pigmentation disorders; vascular malformations.

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References

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