Recent Progress of Photoswitchable Fluorescent Diarylethenes for Bioimaging

Abstract

Photochromic diarylethene has attracted broad research interest in optical applications owing to its excellent fatigue resistance and unique bistability. Photoswitchable fluorescent diarylethene become a powerful molecular tool for fluorescence imaging recently. Herein, the recent progress on photoswitchable fluorescent diarylethenes in bioimaging is reviewed. We summarize the structures and properties of diarylethene fluorescence probes and emphatically introduce their applications in bioimaging as well as super-resolution imaging. Additionally, we highlight the current challenges in practical applications and provide the prospects of the future development directions of photoswitchable fluorescent diarylethene in the field of bioimaging. This comprehensive review aims to stimulate further research into higher-performance photoswitchable fluorescent molecules and advance their progress in biological application.

Keywords: Bioimaging; Diarylethene; Fluorescence photoswitching; Photochromism; Super-resolution imaging.