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Review
. 2024 Nov:101:102481.
doi: 10.1016/j.arr.2024.102481. Epub 2024 Sep 3.

Pathogenesis, diagnostics, and therapeutics for Alzheimer's disease: Breaking the memory barrier

Pushpa Tryphena Kamatham  1 , Rashi Shukla  1 , Dharmendra Kumar Khatri  2 , Lalitkumar K Vora  3
Affiliations
Free article
Review

Pathogenesis, diagnostics, and therapeutics for Alzheimer's disease: Breaking the memory barrier

Pushpa Tryphena Kamatham et al. Ageing Res Rev. 2024 Nov.
Free article

Abstract

Alzheimer's disease (AD) is the most common cause of dementia and accounts for 60-70 % of all cases. It affects millions of people worldwide. AD poses a substantial economic burden on societies and healthcare systems. AD is a progressive neurodegenerative disorder characterized by cognitive decline, memory loss, and impaired daily functioning. As the prevalence of AD continues to increase, understanding its pathogenesis, improving diagnostic methods, and developing effective therapeutics have become paramount. This comprehensive review delves into the intricate mechanisms underlying AD, explores the current state of diagnostic techniques, and examines emerging therapeutic strategies. By revealing the complexities of AD, this review aims to contribute to the growing body of knowledge surrounding this devastating disease.

Keywords: Alzheimer's Disease; Artificial Intelligences; Diagnostics; Future, therapeutics; Machine Learning.

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Conflict of interest statement

Declaration of Competing Interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.