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Review
. 2024 Oct;104(5):965-974.
doi: 10.1016/j.suc.2024.03.003. Epub 2024 Apr 23.

Pancreas Cyst Diagnosis and Advances in Cyst Fluid Analysis

Tommaso Pollini  1 , Letizia Todeschini  1 , Ajay V Maker  2
Affiliations
Review

Pancreas Cyst Diagnosis and Advances in Cyst Fluid Analysis

Tommaso Pollini et al. Surg Clin North Am. 2024 Oct.

Abstract

Pancreatic Cystic Neoplasms (PCN) represent a diverse group of tumors, some of which may progress to pancreatic cancer. Considering their high prevalence in the general population, the development of reliable biomarkers is crucial. The ideal biomarker will accurately diagnose the subtype of PCN and assess the risk of high-grade dysplasia or invasive cancer. Cyst fluid analysis has emerged as a promising approach to accomplish this goal, yet no single marker has yet gained unanimous support for routine inclusion in PCN evaluation.

Keywords: Cyst fluid; IPMN; Intraductal papillary mucinous neoplasms; Pancreatic cancer; Pancreatic cystic neoplams.

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Conflict of interest statement

Disclosure A.V. Maker is an inventor of record on the following pending or issued patent: WO2018183603A1 (PCT/US2018/025,027). T. Pollini and L. Todeschini have no conflict of interest. Funding Authors acknowledge the support of the Inner Child Foundation and the Shorenstein Foundation.

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