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. 2025;26(2):302-311.
doi: 10.2174/0113892010328741240828093859.

Correlation between Honey Parameters and Wound Healing Properties: The Case of Piedmont (Italy) Samples

Simona Martinotti  1 , Gregorio Bonsignore  1 , Mauro Patrone  1 , Elia Ranzato  1
Affiliations

Correlation between Honey Parameters and Wound Healing Properties: The Case of Piedmont (Italy) Samples

Simona Martinotti et al. Curr Pharm Biotechnol. 2025.

Abstract

Introduction: Honey possesses several positive properties, making it effective in wound healing mechanisms. However, very little information is available on the different honey types for wound healing activity.

Method: In the first "Academy of Sciences", a public engagement project with high school students, we assessed the properties of thirteen kinds of honey from the Piedmont area (Nord West Italy). In particular, we characterized the color intensity (by Pfund scale), total phenolic content (TPC), total flavonoid content (TFC), H2O2 production, and wound closure rate.

Results: Then, we tried to verify the presence of a correlation between these parameters, finding a positive correlation between H2O2 and wound closure rate.

Conclusion: These data pave the way to characterize different types of Italian honey to completely understand its potential.

Keywords: H2O2; Honey; pFund scale.; scratch assay; total flavonoid content; total phenolic content; wound closure rate.

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