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Editorial
. 2024 Jul 25;86(9):4966-4968.
doi: 10.1097/MS9.0000000000002409. eCollection 2024 Sep.

FDA approval of Casgevy and Lyfgenia: a dual breakthrough in gene therapies for sickle cell disease

Zainab Syyeda Rahmat  1 , Mohammad Haris Ali  2 , Muhammad Talha  2 , Md Al Hasibuzzaman  3
Affiliations
Editorial

FDA approval of Casgevy and Lyfgenia: a dual breakthrough in gene therapies for sickle cell disease

Zainab Syyeda Rahmat et al. Ann Med Surg (Lond). .
No abstract available

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Conflict of interest statement

The authors certify that they have NO affiliations with or involvement in any organization or entity with any financial interest. The authors declare that they have no conflicts of interest.Sponsorships or competing interests that may be relevant to content are disclosed at the end of this article.

References

    1. FDA News Release. 8 Dec 2023. FDA Approves First Gene Therapies to Treat Patients with Sickle Cell Disease. U.S. Food and Drug Administration. FDA. https://www.fda.gov/news-events/press-announcements/fda-approves-first-g...
    1. Leibovitch JN, Tambe AV, Cimpeanu E, et al. . l-glutamine, crizanlizumab, voxelotor, and cell-based therapy for adult sickle cell disease: hype or hope? Blood Rev 2022;53:100925. - PubMed
    1. Piel FB, Hay SI, Gupta S, et al. . Global burden of sickle cell anaemia in children under five, 2010–2050: modelling based on demographics, excess mortality, and interventions. PLoS Med 2013;10:e1001484. - PMC - PubMed
    1. Sickle Cell Disease. 15 May 2024. Data and Statistics on Sickle Cell Disease. U.S. Centers for Disease Control and Prevention, CDC. https://www.cdc.gov/sickle-cell/data/index.html
    1. Sebastiani P, Nolan VG, Baldwin CT, et al. . A network model to predict the risk of death in sickle cell disease. Blood 2007;110:2727–2735. - PMC - PubMed

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