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Review
. 2024 Jul 12:29:35.
doi: 10.4103/jrms.jrms_509_23. eCollection 2024.

Diabetic peripheral arterial disease in COVID-19 pandemic

Meral Ekim  1 , Hasan Ekim  2 , Gökhan Doğukan Akarsu  3   4
Affiliations
Review

Diabetic peripheral arterial disease in COVID-19 pandemic

Meral Ekim et al. J Res Med Sci. .

Abstract

Both diabetes and peripheral arterial disease (PAD) have complex interactions with COVID-19. PAD is one of the most important underlying factors in the development of diabetic foot. The COVID-19 pandemic has also caused an increase in cardiovascular complications in those with chronic diseases, including diabetics, due to both the thrombophilic course of the viral disease and the lockdown measures applied for prevention. Since both COVID-19 and diabetes mellitus predispose to thrombosis, PAD is likely to have a more severe course in diabetic patients with COVID-19. The aim of our study is to discuss the complications, prophylaxis, and treatment of PAD, which is a serious complication of diabetes, during the pandemic period.

Keywords: Amputation; COVID-19; diabetes mellitus; peripheral arterial disease.

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Conflict of interest statement

There are no conflicts of interest.

Figures

Figure 1
Figure 1
Livedo reticularis on the lower limbs in a diabetic patient
Figure 2
Figure 2
Intraoperative photograph showing the saphenous vein bypass graft in a diabetic patient with severe peripheral artery disease
See this image and copyright information in PMC

References

    1. Marso SP, Hiatt WR. Peripheral arterial disease in patients with diabetes. J Am Coll Cardiol. 2006;47:921–9. - PubMed
    1. Demelo-Rodríguez P, Cervilla-Muñoz E, Ordieres-Ortega L, Parra-Virto A, Toledano-Macías M, Toledo-Samaniego N, et al. Incidence of asymptomatic deep vein thrombosis in patients with COVID-19 pneumonia and elevated D-dimer levels. Thromb Res. 2020;192:23–6. - PMC - PubMed
    1. Putko RM, Bedrin MD, Clark DM, Piscoya AS, Dunn JC, Nesti LJ. SARS-CoV-2 and limb ischemia: A systematic review. J Clin Orthop Trauma. 2021;12:194–9. - PMC - PubMed
    1. Parvar SL, Fitridge R, Dawson J, Nicholls SJ. Medical and lifestyle management of peripheral arterial disease. J Vasc Surg. 2018;68:1595–606. - PubMed
    1. Trunfio R, Deslarzes-Dubuis C, Buso G, Fresa M, Brusa J, Stefanescu A, et al. The effects of COVID-19 pandemic on patients with lower extremity peripheral arterial disease: A near miss disaster. Ann Vasc Surg. 2021;77:71–8. - PMC - PubMed

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