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. 2024 Jul 20;27(9):110539.
doi: 10.1016/j.isci.2024.110539. eCollection 2024 Sep 20.

Kaspar Hauser's alleged noble origin - New molecular genetic analyses resolve the controversy

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Kaspar Hauser's alleged noble origin - New molecular genetic analyses resolve the controversy

Walther Parson et al. iScience. .

Abstract

Kaspar Hauser's parentage has been the subject of research and debate for nearly 200 years. As for his possible aristocratic descent through the House of Baden, there is suspicion that he was swapped as a baby, kidnapped, and kept in isolation to bring a collateral lineage to the throne. In the last 28 years, various genetic analyses have been carried out to investigate this possible aristocratic origin. Previous results using less sensitive Sanger and electrophoresis-based methods were contradictory, and moreover, the authenticity of some samples was disputed, thus leaving the question open. Our analyses using modern capture- and whole genome-based massively parallel sequencing techniques reveal that the mitochondrial DNA haplotypes in different samples attributed to Kaspar Hauser were identical, demonstrating authenticity for the first time, and clearly different from the mitochondrial lineage of the House of Baden, which rules out a maternal relationship and thus the widely believed "Prince theory".

Keywords: History; Molecular genetics; Techniques in genetics.

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Conflict of interest statement

The authors declare no competing interests.

Figures

None
Graphical abstract
Figure 1
Figure 1
Portrait of Kaspar Hauser by Johann Kreul (published by Anselm Ritter von Feuerbach, Dollfuß 1832)
Figure 2
Figure 2
Extract of the genealogical tree of the House of Baden showing the position of the prince who was allegedly transformed to Kaspar Hauser

References

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    1. Daumer G.F. Verlag von Alfred Coppenrath; 1873. Kaspar Hauser. Sein Wesen, seine Unschuld, seine Erduldungen und sein Ursprung in neuer, gründlicher Erörterung und Nachweisung.
    1. Pies H. Verlag C. Brügel & Sohn; 1966. Kaspar Hauser. Eine Dokumentation.
    1. Merker F.,C. L. W. Krause’sche Buchhandlung; 1831. Nachrichten über Caspar Hauser, aus authentischen Quellen und Betrachtungen über deren Beweiskraft für die Einkerkerungs-Geschichte des Jünglings.
    1. Stanhope P.H. Materialien zur Geschichte Kaspar Hausers. Akademische Buchhandlung von J. E. B. Mohr, Heidelberg; 1835.

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