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Observational Study
. 2024 Sep 11;6(9):e1149.
doi: 10.1097/CCE.0000000000001149. eCollection 2024 Sep 1.

The Discover In-Hospital Cardiac Arrest (Discover IHCA) Study: An Investigation of Hospital Practices After In-Hospital Cardiac Arrest

Luke Andrea  1 , Nathaniel S Herman  1 , Jacob Vine  2 , Katherine M Berg  2   3 , Saiara Choudhury  4 , Mariana Vaena  5 , Jordan E Nogle  6 , Saleem M Halablab  7 , Aarthi Kaviyarasu  7 , Jonathan Elmer  8   9   10 , Gabriel Wardi  11   12 , Alex K Pearce  12 , Conor Crowley  13 , Micah T Long  14 , J Taylor Herbert  15 , Kipp Shipley  16 , Brittany D Bissell Turpin  17   18 , Michael J Lanspa  19 , Adam Green  20   21 , Shekhar A Ghamande  22 , Akram Khan  23 , Siddharth Dugar  24 , Aaron M Joffe  25 , Michael Baram  26 , Cooper March  27 , Nicholas J Johnson  27   28 , Alexander Reyes  29 , Krassimir Denchev  30 , Michael Loewe  31   32 , Ari Moskowitz  1 ; Society of Critical Care Medicine’s Discovery, the Critical Care Research Network DISCOVER In-Hospital Cardiac Arrest (DISCOVER IHCA): Investigator Group
Collaborators, Affiliations
Observational Study

The Discover In-Hospital Cardiac Arrest (Discover IHCA) Study: An Investigation of Hospital Practices After In-Hospital Cardiac Arrest

Luke Andrea et al. Crit Care Explor. .

Abstract

Importance: In-hospital cardiac arrest (IHCA) is a significant public health burden. Rates of return of spontaneous circulation (ROSC) have been improving, but the best way to care for patients after the initial resuscitation remains poorly understood, and improvements in survival to discharge are stagnant. Existing North American cardiac arrest databases lack comprehensive data on the post-resuscitation period, and we do not know current post-IHCA practice patterns. To address this gap, we developed the Discover In-Hospital Cardiac Arrest (Discover IHCA) study, which will thoroughly evaluate current post-IHCA care practices across a diverse cohort.

Objectives: Our study collects granular data on post-IHCA treatment practices, focusing on temperature control and prognostication, with the objective of describing variation in current post-IHCA practice.

Design, setting, and participants: This is a multicenter, prospectively collected, observational cohort study of patients who have suffered IHCA and have been successfully resuscitated (achieved ROSC). There are 24 enrolling hospital systems (23 in the United States) with 69 individual enrolling hospitals (39 in the United States). We developed a standardized data dictionary, and data collection began in October 2023, with a projected 1000 total enrollments. Discover IHCA is endorsed by the Society of Critical Care Medicine.

Interventions, outcomes, and analysis: The study collects data on patient characteristics including pre-arrest frailty, arrest characteristics, and detailed information on post-arrest practices and outcomes. Data collection on post-IHCA practice was structured around current American Heart Association and European Resuscitation Council guidelines. Among other data elements, the study captures post-arrest temperature control interventions and post-arrest prognostication methods. Analysis will evaluate variations in practice and their association with mortality and neurologic function.

Conclusions: We expect this study, Discover IHCA, to identify variability in practice and outcomes following IHCA, and be a vital resource for future investigations into best-practice for managing patients after IHCA.

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Conflict of interest statement

The authors have disclosed that they do not have any potential conflicts of interest.

Figures

Figure 1.
Figure 1.
Geographic region of participating hospital systems. This figure shows the number of participating hospital systems, and individual hospitals, within each geographic region.
Figure 2.
Figure 2.
Data elements collected for each patient in the Discover In-Hospital Cardiac Arrest (Discover IHCA) study. This figure visually displays the structure of the data elements collected in the Discover IHCA study.
See this image and copyright information in PMC

References

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