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Review
. 2025 Feb;52(3):1200-1209.
doi: 10.1007/s00259-024-06906-4. Epub 2024 Sep 11.

EANM position paper on challenges and opportunities of full-ring 360° CZT bone imaging: it's time to let go of planar whole-body bone imaging

Richard Graham  1 , David Morland  2 , Sarah Cade  3 , Laetitia Imbert  4 , Emmanouil Panagiotidis  5 , Jens Kurth  6 , Frédéric Paycha  7 , Tim Van den Wyngaert  8   9
Affiliations
Review

EANM position paper on challenges and opportunities of full-ring 360° CZT bone imaging: it's time to let go of planar whole-body bone imaging

Richard Graham et al. Eur J Nucl Med Mol Imaging. 2025 Feb.

Abstract

The introduction of smaller footprint, more sensitive Cadmium-Zinc-Telluride (CZT)-based detectors with improved spatial and energy resolution has enabled the design of innovative full-ring 360° CZT SPECT/CT systems (e.g., VERITON® and StarGuide™). With this transformative technology now aiming to become mainstream in clinical practice, several critical questions need to be addressed. This EANM position paper provides practical recommendations on how to use these devices for routine bone SPECT/CT studies, facilitating the transition from traditional planar whole-body imaging and conventional SPECT/CT to these novel systems. In particular, initial guidance is provided on imaging acquisition and reporting workflows, image reconstruction, and CT acquisition parameters. Given the emerging nature of this technology, the available evidence base is still limited, and the proposed adaptations in workflows and scan protocols will likely evolve before being integrated into definitive guidelines. In the meantime, this EANM position paper serves as a comprehensive guide for integrating these advanced hybrid SPECT/CT imaging systems into clinical practice and outlining areas for further study.

Keywords: 360° SPECT/CT; Bone scintigraphy; CZT; Cadmium-Zinc-Telluride; Ring geometry.

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Conflict of interest statement

Declarations. Competing interests: RG has received honoraria from GE Healthcare. The department LI is associated with is a Spectrum Dynamics reference site for the Veriton SPECT/CT. All other authors have no relevant financial or non-financial interests to disclose.

Figures

Fig. 1
Fig. 1
Suggested SPECT/CT reporting workflow
Fig. 2
Fig. 2
Comparison of traditional anterior planar whole-body view and reconstructed pseudoplanar using full-ring 360° CZT SPECT/CT and respective fused Volume Rendering Technique (VRT) image in the same patient with synovitis, acne, pustulosis, hyperostosis, osteitis (SAPHO) syndrome
See this image and copyright information in PMC

References

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