When bigger is better: utilizing large animal models in vein graft surgery to gain insights into endothelial-to-mesenchymal transition

Affiliations

¹ Department of Cell and Chemical Biology, Leiden University Medical Center, Einthovenweg 20, 2333 ZC, Leiden, The Netherlands.
² Nanomaterials and Nanotechnology Research Center (CINN), Spanish National Research Council (CSIC), Health Research Institute of Asturias (ISPA), 33011 Oviedo, Asturias, Spain.

Editorial

Clarissa Becher et al. Cardiovasc Res. 2024.

. 2024 Nov 25;120(14):1651-1653.

doi: 10.1093/cvr/cvae204.

¹ Department of Cell and Chemical Biology, Leiden University Medical Center, Einthovenweg 20, 2333 ZC, Leiden, The Netherlands.
² Nanomaterials and Nanotechnology Research Center (CINN), Spanish National Research Council (CSIC), Health Research Institute of Asturias (ISPA), 33011 Oviedo, Asturias, Spain.

No abstract available

Conflict of interest statement

Conflict of interest: none declared.

Inhibition of endothelial-to-mesenchymal transition in a large animal preclinical arteriovenous fistula model leads to improved remodelling and reduced stenosis.
Xu Y, Korayem A, Cruz-Solbes AS, Chandel N, Sakata T, Mazurek R, Mavropoulos SA, Kariya T, Aikawa T, Yamada KP, D'Escamard V, V'Gangula B, Baker AH, Ma L, Björkegren JLM, Fuster V, Boehm M, Fish KM, Tadros R, Ishikawa K, Kovacic JC. Xu Y, et al. Cardiovasc Res. 2024 Nov 25;120(14):1768-1779. doi: 10.1093/cvr/cvae157. Cardiovasc Res. 2024. PMID: 39056563 Free PMC article.